Association of pentraxin in periodontitis patients with coronary artery disease.

Objectives: Pentraxin 3 (PTX3) is a biomarker, associated with the pathogenesis of Periodontitis and coronary artery disease (CAD) individually, but their role in patients with both diseases remains unclear. The current study aims to evaluate the association of PTX in patients with concomitant periodontitis and CAD.

Materials And Methods: In a case-control study, 240 participants were selected and divided into four groups.

Evidence linking the association of periodontal viruses and pentraxins in periodontitis patients with coronary artery disease.

Background: Although there is ample evidence in the literature supporting a significant positive association between key periodontal pathogens and established inflammatory markers of periodontitis and coronary artery disease (CAD), their exact role remain unclear. Especially, the role of viruses in the etiology and specific biomarkers have not been validated. Thus, the current study aims to evaluate the role of periodontal viruses such as Epstein-Barr virus (EBV), cytomegalovirus (CMV), and herpes simplex virus (HSV), as well as the inflammatory marker pentraxin-3 (PTX3), and to analyze their association with CAD.

Interdental Papillary Reconstruction by Microtunnelling Technique Using Autologous Biomatrices-A Randomised Controlled Clinical Trial.

Background and objectives: The study aimed to evaluate and compare the amount of papillary gain and black triangle height reduction after intervention with a microtunnelling technique with either Connective tissue graft (CTG) or Platelet-rich fibrin (PRF) as a biomatrix at 6 months using a microsurgical approach. Materials and Methods: Twenty-six patients with interdental papillary loss were included in the study. The patients were selected randomly for the study groups with thirteen patients in each group: a control group where CTG was utilised as a matrix, and a test group where PRF was utilised as a matrix, for interdental papillary reconstruction.

Evaluation of the periodontal viruses in cardiovascular patients associated with periodontitis.

Objectives: The current study aimed in evaluating the prevalence of Epstein-Barr virus (EBV), cytomegalovirus (CMV), and herpes simplex virus (HSV) in periodontitis and/or coronary artery disease (CAD) patients to compare with their healthy controls and insist their significance in the same.

Methodology: Two hundred and forty patients were divided into 4 groups. Non-periodontitis+non-cardiac (NP+NC) = 60 patients, periodontitis+non-cardiac patients (P+NC) = 60 patients, non-periodontitis+cardiac patients (NP+C) = 60 patients, and periodontitis+cardiac (P+C) = 60 patients.

Association of Epstein-Barr virus, cytomegalovirus and lipocalin with periodontitis in type 2 diabetic subjects.

Objective: The current study aims to evaluate and compare the lipocalin, adiponectin and periodontal viruses in the generalized periodontitis patients with and without diabetes mellitus.

Materials And Methods: Seventy subjects were grouped into 35 systemically healthy (GP) and 35 patients with diabetes mellitus (GP+DM). The periodontal parameters, demographic and diabetic variables were evaluated in both the groups.

Evidence revealing the role of T cell regulators (Tregs) in periodontal diseases: A review.

Periodontitis is an inflammatory disease of the periodontium, which is a reflection of the overgrowth of oral commensals. This alteration in the oral microbiota initiates inflammation of the gingiva, which when left untreated, terminates with the resorption of the alveolar bone that may lead to a poor and hopeless prognosis. With upcoming trends in modulating the host's immunity, the role of regulatory T-cells has gained importance.