Characterizing epileptogenic zones EZ (sources responsible of excessive discharges) would assist a neurologist during epilepsy diagnosis. Locating efficiently these abnormal sources among magnetoencephalography (MEG) biomarker is obtained by several inverse problem techniques. These techniques present different assumptions and particular epileptic network connectivity.
View Article and Find Full Text PDFComput Methods Programs Biomed
October 2019
The patterns of brain dynamics were studied during resting state on a macroscopic scale for control subjects and multiple sclerosis patients. Macroscopic brain dynamics is defined after successive coarse-grainings and selection of significant patterns and transitions based on Markov representation of brain activity. The resulting networks show that control dynamics is merely organized according to a single principal pattern whereas patients dynamics depict more variable patterns.
View Article and Find Full Text PDFThe resting state dynamics of the brain shows robust features of spatiotemporal pattern formation but the actual nature of its time evolution remains unclear. Computational models propose specific state space organization which defines the dynamic repertoire of the resting brain. Nevertheless, methods devoted to the characterization of the organization of brain state space from empirical data still lack and thus preclude comparison of the hypothetical dynamical repertoire of the brain with the actual one.
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