Publications by authors named "Abilasha R"
Introduction Most fungal infections are responsive to antifungal therapy. However, failure to diagnose the same can significantly affect the quality of lives of patients. Timely identification of fungal infections and their association with varied demographic and clinical parameters will help in improving the prognosis of the patient.
View Article and Find Full Text PDFArticle Synopsis
- - Oral Squamous Cell Carcinoma (OSCC) is responsible for nearly 90% of oral cancers, and researchers are investigating various factors that may influence treatment outcomes, including vitamin D levels.
- - A study involving 40 subjects (20 OSCC patients and 20 healthy individuals) found that salivary vitamin D3 levels were significantly lower in OSCC patients (39.09 ng/dl) compared to healthy controls (44.49 ng/dl).
- - The findings suggest that vitamin D deficiency may contribute to more aggressive cancer characteristics in OSCC, indicating the potential benefit of vitamin D supplementation during and after treatment to improve patient prognosis.
Background: One of the most prevalent malignancies in India is oral squamous cell carcinoma (OSCC), which is found in more than 90% of cancer cases and has a reduced survival rate of 30%. Matrix metalloproteinases (MMPs) are zinc-containing and calcium-dependent endopeptidases that regulate angiogenesis, migration, and proliferation. MMP-9 in OSCC increases tumor progression through angiogenesis, degrades the basement membrane, and facilitates metastasis by changes in tissue shape.
View Article and Find Full Text PDFEngineered Dex: A promising therapeutic strategy for oral squamous cell carcinoma.
J Stomatol Oral Maxillofac Surg
February 2023
A comprehensive analysis of volatile organic compounds (VOCs) from the exhaled breath sample is termed as breathomics. Breath samples are a complex mixture composed of a multitude of VOCs and other molecules. The analysis of total VOCs in exhaled breath provides a promising tool for the diagnosis of many diseases because it enables the observation of biochemical processes in the body in a non-invasive way.
View Article and Find Full Text PDFThe etiology of dental caries is generally agreed to be a complex problem with many indirect factors that may obscure the direct cause or causes. There is substantial evidence that heredity plays an important role in this disease. Dermatoglyphics is a study that can be used to indicate congenital abnormalities.
View Article and Find Full Text PDF