Red raspberry () supplementation mitigates the effects of a high-fat diet on brain and behavior in mice.

Objectives: Research has shown that berries may have the ability to reverse, reduce, or slow the progression of behavioral dysfunction associated with aging and neurodegenerative disease. In contrast, high-energy and high-fat diets (HFD) may result in behavioral deficits like those seen in aging animals. This research examined whether red raspberry () mitigates the effects of HFD on mouse brain and behavior.

Blueberry supplementation attenuates microglia activation and increases neuroplasticity in mice consuming a high-fat diet.

Objectives: Consuming a high-fat diet (HFD) may result in behavioral deficits similar to those observed in aging animals. Blueberries may prevent and even reverse age-related alterations in neurochemistry and behavior. It was previously demonstrated that middle-aged mice fed HFD had impaired memory; however, supplementation of HFD with blueberry reduced these memory deficits.