Insights about personality traits and cognitive performance and decline in adults 51-59 Years old from the Wisconsin longitudinal study.

Objectives: To delineate midlife personality dimensions of early cognitive change in an age-homogenous sample of U.S. older adults.

Robust normative standards for the California Verbal Learning Test (CVLT) ages 60-89: A tool for early detection of memory impairment.

: To detect cognitive "impairment," neuropsychologists rely on normative data to compare patient performance to "normal" peers. However, the true normality of normative samples may be called into question given the high prevalence of preclinical proteinopathies amongst clinically normal older adults. Given its common use in memory clinics, we aimed to develop a robust California Verbal Learning Test (CVLT) normative standard reflecting only the most cognitively stable sample of older adults available.

Association of Blood and Cerebrospinal Fluid Tau Level and Other Biomarkers With Survival Time in Sporadic Creutzfeldt-Jakob Disease.

Importance: Fluid biomarkers that can predict survival time in sporadic Creutzfeldt-Jakob disease (sCJD) will be critical for clinical care and for treatment trials.

Objective: To assess whether plasma and cerebrospinal fluid (CSF) biomarkers are associated with survival time in patients with sCJD.

Design, Setting, And Participants: In this longitudinal cohort study, data from 193 patients with probable or definite sCJD who had codon 129 genotyping referred to a tertiary national referral service in the United States were collected from March 2004 to January 2018.

Attentional effects of hand proximity occur later in older adults: Evidence from event-related potentials.

Research with young adults has shown hand proximity biases attention both early (by the time stimuli are categorized as relevant for action) and later, selectively for goal-relevant-stimuli. We examined age-related changes in this multisensory integration of vision and proprioception by comparing behavior and event-related potentials (ERPs) between younger and older adults. In a visual detection task, the hand was placed near or kept far from target and nontarget stimuli matched for frequency and visual features.