Publications by authors named "Abigail N Rankine"
Background: Nearly 66% of occurrences of gastric cancer (GC), which has the second-highest death rate of all cancers, arise in developing countries. In several cancers, the predictive significance of inflammatory markers has been established.
Aim: To identify clinical characteristics and develop a specific nomogram to determine overall survival for GC patients.
Background: We aimed to investigate the association between the number of examined lymph nodes (ELNs) and accurate nodal staging and long-term survival in Siewert type II-III Adenocarcinoma of the Esophagogastric Junction (AEG) by using large population-based databases and determined the optimal ELN number threshold.
Methods: Data on Stage I-III Siewert type II-III AEG patients from 2010 to 2014 respectively from the United States (US) SEER database and a Chinese large medical center institutional registry were analyzed for correlation between the ELN number and stage migration (node negative-to-positive) and overall survival (OS) by using multivariable-adjusted logistic and Cox regression models, respectively. The series of odds ratios (ORs), and hazard ratios (HRs) were fitted with a LOWESS smoother, and the structural breakpoints were determined by Chow test.
Background: In recent years, the incidence of types II and III adenocarcinoma of the esophagogastric junction (AEG) has shown an obvious upward trend worldwide. The prognostic prediction after radical resection of AEG has not been well established.
Aim: To establish a prognostic model for AEG (types II and III) based on routine markers.
Article Synopsis
- - Emerging research indicates that non-coding RNAs (ncRNAs), particularly long non-coding RNAs (lncRNAs), play critical roles in tumor development, including head and neck squamous cell carcinoma (HNSCC).
- - LncRNAs, which are RNA transcripts longer than 200 nucleotides, are involved in various biological processes linked to cancer, affecting growth, spread, and overall outlook in HNSCC patients.
- - The review discusses the mechanisms regulating lncRNAs in cancer and emphasizes their potential as biomarkers for diagnosing and treating HNSCC, while noting that more research is needed in this area.