Plasma cytokine and growth factor response to acute psychosocial stress in major depressive disorder.

Background: Pro-inflammatory cytokines such as interleukin (IL)-6 and tumor necrosis factor (TNF)-α are elevated in response to psychosocial stress; however, less is known about other inflammatory markers.

Methods: We explored response to the Trier Social Stress Test (TSST) of 16 cytokines and growth factors in patients with major depressive disorder (MDD, n = 12) vs. healthy volunteers (HV, n = 16).

Complete remission of unresectable hepatocellular carcinoma treated with reduced dose of sorafenib: a case report.

Hepatocellular carcinoma (HCC) is a highly aggressive cancer. For patients who are diagnosed with advanced stage disease that are not surgical candidates, the disease is universally lethal. Advance has been made to extend survival with molecular target therapy, but durable complete responses are extremely rare.

The resident scholar program: a research training opportunity for internal medicine house staff.

Background: Housestaff research training is a challenging task that is complicated by the lack of a structured process and dedicated time. The Resident Scholar Program (RSP) at the University of Cincinnati, Department of Internal Medicine was created to overcome these challenges.

Methods: Interested internal medicine house staff are required to submit an application to the residency research director including a project description signed by a faculty mentor.

The clinical use of karyotyping spontaneous abortions.

Objective: The objective of this study was to assess the clinical use of routinely karyotyping spontaneous abortion material.

Study Design: We retrospectively reviewed the records of the Pittsburgh Cytogenetics Laboratory from January 1, 1998, to December 31, 2001, for all tissues from spontaneous losses at 20 weeks' gestation or less for which complete medical records were available.

Results: There were 517 submitted samples of which 28 (5.

Parental evaluation of informing interviews for cleft lip and/or palate.

Objective: This study was conducted to record subjective information concerning parental experiences and preferences with regard to informing interviews for cleft lip and/or palate. The analysis of these data was intended to help informants improve the way in which such conversations are conducted.

Methods: The study used a self-administered questionnaire.