Background: Non-invasive ventilation (NIV) is a valuable treatment in the management of acute hypercapnic respiratory failure. NIV is not without risks. One such adverse effect is the development of pressure ulcers over the nasal bridge which have an incidence of up to 20% of patients requiring NIV in this setting.
View Article and Find Full Text PDFIntroduction: A high prevalence of OSA has been observed in asthma populations, with detrimental impact on clinical outcomes.
Aim: To determine if CPAP treatment of co-existing OSA improves asthma-related symptoms and quality of life.
Methods: Literature review of EMBASE and MEDLINE databases prior to July 2017.
Objective: Bronchial asthma and obstructive sleep apnoea (OSA) are common respiratory disorders that can co-exist. The strength of this association, and also the impact of OSA on asthma-related clinical outcomes remain unclear.
Data Sources: Literature review was performed in EMBASE and MEDLINE databases.
Background: Bronchial airway inflammation is the hallmark of asthma, which may be driven by an imbalance between oxidative stress and antioxidant defenses. Antioxidants deficiency may play a role, but this has remained unconfirmed.
Objective: To evaluate the oxidative stress burden and antioxidants defenses in patients with increasing asthma severity.