Phytochemical profile and antimicrobial activity of extracts against oral microorganisms.

Introduction: The growing problem of antimicrobial resistance on a global scale has highlighted the need to investigate alternative antimicrobial agents with reduced side effects. Plant-derived secondary metabolites have emerged as potential contenders in tackling this challenge. , a perennial plant, has traditionally been utilized for the treatment of gum boils, toothaches, and infections.

Combinatorial effects of hydroxyapatite and Tualang honey on medication-related osteonecrosis of the jaw (MRONJ): An in vitro study.

Background: Medication-related osteonecrosis of the jaw (MRONJ) is a severe complication associated with prolonged bisphosphonate therapy. Increasing evidence shows that mucosal damage plays an important role in the pathogenesis of MRONJ. This study investigates the combinatorial effects of hydroxyapatite with Tualang honey on cell viability and wound healing in MRONJ.

The effect of extra virgin olive oil (EVOO) on fat mass and fat-free mass for breastfeeding mothers (0-24 months) in Makassar City, Indonesia.

Background: Extra Virgin Olive Oil (EVOO) is a fat source classified as monounsaturated fatty acid. Previous studies have shown that 47.5% of breastfeeding mothers have less fat intake when compared to the Adequacy of Nutrition Rate (RDA).

Rational design of N-doped C-encapsulated flower-like nickel-based heterostructured microsphere anodes for high-capacity and stable lithium storage.

Designing a unique morphology and nanoarchitecture with a heterostructure is regarded as an efficient strategy to achieve lithium-ion batteries (LIBs) with high capacity and cycle life. Herein, N-doped C-encapsulated flower-like NiS/Ni(BO) heterostructures (NiS/Ni(BO)/NC) with a core-shell morphology are successfully synthesized by a facile general method to improve the rate performance and prolong the cycle life of LIBs. The coated NC layer and core-shell structure with elasticity can relieve the volume expansion during the lithiation/delithiation process to strengthen the stability of the structure.

Biochemical, Toxicological, and in Silico Aspects of Trillium govanianum Wall. ex D.Don (Trilliaceae): A Rich Source of Natural Bioactive Compounds.

Trillium govanianum is a high-value medicinal herb, having multifunctional traditional and culinary uses. The present investigation was carried out to evaluate the phytochemical, biological and toxicological parameters of the T. govanianum Wall.

The clinical implications of Porphyromonas gingivalis and its detection methods - a systematic review.

Introduction: Mounting evidence has shown the significant correlation between periodontitis and the development of other comorbidities, such as cardiovascular disease due to periodontopathogenic bacterial migration and colonisation. As the main etiologic agent of periodontitis, the role of Porphyromonas gingivalis (P. gingivalis) has been widely explored as the main culprit and its early detection is crucial to control the exacerbation of diseases.

A new perspective on Alzheimer's disease: microRNAs and circular RNAs.

microRNAs (miRNAs) play a multifaceted role in the pathogenesis of Alzheimer's disease (AD). miRNAs regulate several aspects of the disease, such as Aβ metabolism, tau phosphorylation, neuroinflammation, and synaptic function. The dynamic interaction between miRNAs and their target genes depends upon various factors, including the subcellular localization of miRNAs, the relative abundance of miRNAs and target mRNAs, and the affinity of miRNA-mRNA interactions.

Contextual Cluster-Based Glow-Worm Swarm Optimization (GSO) Coupled Wireless Sensor Networks for Smart Cities.

The cluster technique involves the creation of clusters and the selection of a cluster head (CH), which connects sensor nodes, known as cluster members (CM), to the CH. The CH receives data from the CM and collects data from sensor nodes, removing unnecessary data to conserve energy. It compresses the data and transmits them to base stations through multi-hop to reduce network load.

Investigation of resource curse hypothesis: the role of renewable energy and urbanization in realizing environmental sustainability in China.

This research investigates the resource curse hypothesis and environmental sustainability by integrating China's natural resources, renewable energy, and urbanization. However, the EKC N shape describes the complete picture of the EKC hypothesis for the growth-pollution relationship. The findings of FMOLS and DOLS show that economic expansion positively drives carbon dioxide emissions in the beginning, then negatively so after the target level of growth is reached.

Identification of time-varying wetlands neglected in Pakistan through remote sensing techniques.

Aside from Ramsar Convention awareness programs, the concept of wetlands is mostly ignored in developing countries. Wetland ecosystems are essential to hydrological cycles, ecosystem diversity, climatic change, and economic activity. Under the Ramsar Convention, there are 2414 wetlands that are internationally recognized, and Pakistan is home to 19 of them.

Behavioural, genomics and proteomic approach to examine Alzheimer's disease in zebrafish.

Globally around 24 million elderly population are dealing with dementia, and this pathological characteristic is commonly seen in people suffering from Alzheimer's disease (AD). Despite having multiple treatment options that can mitigate AD symptoms, there is an imperative call to advance our understanding of the disease pathogenesis to unfold disease-modifying treatments/therapies. To explore the driving mechanisms of AD development, we stretch out further to study time-dependant changes after Okadaic acid (OKA)-induced AD-like conditions in zebrafish.

Sensory‑motor performance and neurochemical effects in the cerebral cortex of brain‑derived neurotrophic factor heterozygous mice fed a high‑cholesterol diet.

Reports suggest that a high‑cholesterol diet may induce neuroinflammation, oxidative stress, and neurodegeneration in brain tissue. Brain‑derived neurotrophic factor (BDNF) might play a role in protecting against changes induced by high cholesterol. We aimed to assess behavioral correlates and biochemical alterations in the motor and sensory cortices following a high‑cholesterol diet under normal and reduced BDNF concentrations.

The anti-melanogenic properties of Swietenia macrophylla king.

Fair flawless skin is the goal for some cultures and the development of irregular skin pigmentation is considered an indication of premature skin aging. Hence, there is a rising demand for skin whitening cosmetics. Thus, this research will be focusing on discovering the anti-pigmentation properties of Swietenia macrophylla seeds.

Teaching Nature and Architecture: Student-Led Account of Biomimicry Innovations in the Tropics.

The built environment has a huge carbon footprint, and decarbonizing it is essential in driving our sustainability efforts. We take the approach of biomimicry by working with Master of Architecture students from Taylor's University in Malaysia. The students partake in a 14-week Nature and Architecture design module at the university where they develop biomimicry solutions for the built environment with a focus on sustainability.

Transformation of Children's Paintings into Public Art to Improve Public Spaces and Enhance People's Happiness.

Characteristics of children's paintings have been suggested considered for application in public art since they are known to positively evoke a sense of well-being when people see them. This study aims to understand the impact of artistic features from children's drawings on people's well-being; then analyzing the adaptive design principles of 3D public art featuring children's paintings on people's happiness; and finally, exploring the influence of 3D public art featuring children's paintings on improving public spaces and enhancing people's well-being. The results lead to proposing a conceptual framework for public artworks in public spaces for improving people's happiness.

Smart Health Monitoring System with Wireless Networks to Detect Kidney Diseases.

It is essential to change health services from a hospital to a patient-centric platform since medical costs are steadily growing and new illnesses are emerging on a worldwide scale. This study provides an optimal decision support system based on the cloud and Internet of Things (IoT) for identifying Chronic Kidney Disease (CKD) to provide patients with efficient remote healthcare services. To identify the presence of medical data for CKD, the proposed technique uses an algorithm named Improved Simulated Annealing-Root Mean Square -Logistic Regression (ISA-RMS-LR).

Situation of snakebite, antivenom market and access to antivenoms in ASEAN countries.

Introduction: Snakebite envenoming is a neglected tropical disease posing public health challenges globally. The Association of Southeast Asian Nations (ASEAN) countries are among the tropical regions with disproportionately high incidence of snakebite. Hence, this study aimed to review the situation of snakebite, antivenom market and access to antivenoms in ASEAN.

Investigating Genetic and Other Determinants of First-Onset Myocardial Infarction in Malaysia: Protocol for the Malaysian Acute Vascular Events Risk Study.

Background: Although the burden of premature myocardial infarction (MI) is high in Malaysia, direct evidence on the determinants of MI in this multi-ethnic population remains sparse.

Objective: The Malaysian Acute Vascular Events Risk (MAVERIK) study is a retrospective case-control study established to investigate the genomic, lipid-related, and other determinants of acute MI in Malaysia. In this paper, we report the study protocol and early results.

ICT, renewable energy, financial development, and CO emissions in developing countries of East and South Asia.

This study aims to analyze the impact of ICT, renewable energy consumption, and financial development on CO emissions in selected developing countries of East and South Asia. Using panel data spanning 1985-2020, Pooled Mean Group (PMG) estimator is used to analyze the short-run and long-run effects. Results suggest that ICT and financial development positively contribute to the degradation of the environment in the long run, while their impact on CO emissions is insignificant in the short run.

Palyno-anatomical microscopic characterization of selected species of Boraginaceae and Fabaceae.

Palyno-anatomical characterization of some selected species of Boraginaceae and Fabaceae using light microscopy (LM) and scanning electron microscopy (SEM) was conducted. Six species of them belongs to four genera of family Boraginaceae and other six species belongs to four genera of Fabaceae. The current study aimed to investigate palyno-anatomical features for correct identification and taxonomic significance.

Radiosensitization effects by bismuth oxide nanorods of different sizes in megavoltage external beam radiotherapy.

Background: Nanotechnology application has successfully reached numerous scientific breakthroughs including in radiotherapy. However, the clinical application of nanoparticles requires more diligent research primarily on the crucial parameters such as nanoparticle sizes. This study is aimed to investigate the influence of bismuth oxide nanorod (BiO-NR) sizes on radiosensitization effects on MCF-7 and HeLa cell lines for megavoltage photon and electron beam radiotherapy.