Publications by authors named "Abi Janet Riley"
Background: Mycobacterium tuberculosis culturing remains the gold standard for laboratory diagnosis of tuberculosis. Tuberculosis remains a great public health problem in developing countries like The Gambia, as most of the methods currently used for bacterial isolation are either time-consuming or costly.
Objective: To evaluate the Kudoh swab method in a West African setting in Gambia, with a particular focus on the method's performance when culturing Mycobacterium africanum West Africa 2 (MAF2) isolates.
Article Synopsis
- Blood-based biomarkers could provide a more effective way to monitor treatment response in active tuberculosis compared to traditional sputum-based methods.
- In a study with twenty adults, immune responses were measured before and after two months of standard TB treatment, revealing key differences in T cell activation between fast and slow responders.
- Findings suggest that while treatment may reduce T cell activation markers, the initial levels of these markers could help predict how quickly a patient responds to treatment.
The geographically restricted Mycobacterium africanum lineages (MAF) are primarily found in West Africa, where they account for a significant proportion of tuberculosis. Despite this phenomenon, little is known about the co-evolution of these ancient lineages with West Africans. MAF and M.
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