Uric acid and cardiovascular disease risk reclassification: findings from NHANES III.

Background: The studied associations between serum uric acid (sUA) and cardiovascular disease (CVD) events have been controversial. We sought to evaluate the association between sUA and CVD mortality, including its ability to reclassify risk in a multiethnic nationally representative population free of clinical CVD and diabetes at baseline.

Methods: The study cohort included 11,009 adults enrolled as a part of the National Health and Nutrition Examination Survey (NHANES) III.