Publications by authors named "Abhishek Mandal"

Fish, being highly sensitive to changes in the physico-chemical parameters of water, are good indicators of contamination. Teesta, a prominent northern West Bengal River system, is increasingly contaminated due to anthropogenic activities. This study aims to determine agricultural pesticide contamination and its genotoxic impact on the resident fish, Pethia conchonius, as an experimental organism.

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Insecticidal potential of seven commonly available alkaloids against melon thrips (Thrips palmi Karny) was investigated through in vivo experiments and the bioactivity was explained via in silico approaches. In vivo screening showed highest mortality of T. plami larvae for reserpine (43%), closely followed by tropinone (41%) after 24 h of incubation.

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Article Synopsis
  • The development of alcohol-associated liver disease (ALD) involves multiple factors, including intracellular processes, inflammation, and fibrosis stemming from early liver injury due to alcohol consumption.
  • Alcohol metabolism and stress within liver cells, along with factors from the gut, cause damage to liver and immune cells, leading to the production of harmful signaling molecules.
  • Alcohol-associated hepatitis (AH), a severe form of liver failure in chronic alcohol users, is not well understood, indicating a need for more research to create effective treatments.
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In the present study, persistence and degradation of tembotrione, a triketone herbicide, was studied in loamy soil collected from maize field. Effects of organic amendments, moistures and temperatures on tembotrione dissipation were evaluated. Soil samples were processed according to the modified QuEChERS involving dichloromethane solvent and MgSO without PSA.

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Fall armyworm (FAW), (J.E. Smith), a threat to maize production systems, is a polyphagous pest of global significance.

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Microplastic (MP) pollution has engulfed global aquatic systems, and the concerns about microplastic translocation and bioaccumulation in fish and other aquatic organisms are now an unpleasant truth. In the past few years, MP pollution in freshwater systems, particularly rivers and subsequently in freshwater organisms, especially in fish, has caught the attention of researchers. Rivers provide livelihood to approximately 40 % of the global population through food and potable water.

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A series of 16 novel prenylated chalcones () was synthesized by microwave-assisted green synthesis using 5-prenyloxy-2-hydroxyacetophenone and different benzaldehydes. Comparisons were also performed between the microwave and conventional methods in terms of the reaction times and yields of all compounds, where the reaction times in the microwave and conventional methods were 1-4 min and 12-48 h, respectively. The synthesized compounds were characterized using different spectroscopic techniques, including IR, H-NMR, C-NMR, and LC-HRMS.

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Article Synopsis
  • The study focuses on creating phenathroimidazole derivatives for efficient deep-blue light emitting diodes (LEDs).
  • Two specific compounds, Cz-SBDPI and TPA-SBDPI, were synthesized, which show high thermal stability and superior optical and electrical properties.
  • The Cz-SBDPI device outperforms the TPA-based one in brightness and efficiency, indicating that these donor-acceptor emitters could be cost-effective materials for high-performance OLED devices.
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Collagen-based nanobiocomposites can reabsorb and are biodegradable. These properties are effectively controlled by the number of cross-links. This study demonstrates an effortless and proficient approach for the functionalization of FeO NPs for cross-linking collagen obtained from biowaste, viz.

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In this study, for the first time, we evaluated microplastic contamination in water, beach sand, and fish samples collected from the seven most famous and crowded beaches of the eastern coast of India, which cover around 1200 km. The average number of microplastics found was 80 ± 33 microplastics/m and 4 ± 2 microplastics/kg dry weight with a numerical abundance of polyethylene and polystyrene for water and sand samples, respectively. The polymer hazard index score, which represents the severity of the microplastics scenario in the studied locations, depicts that this coastline falls under hazard levels IV and V (most hazardous) for water and sand samples, respectively.

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This study analyzed microplastics in the gastrointestinal tract of Siberian dace (Leuciscus leuciscus subsp. baicalensis (Dybowski, 1874)) in the remote Yenisei tributary of the Nizhnyaya (Lower) Tunguska River (Siberia, Russia). µRaman analysis showed that 60% of the fish from two different sites had ingested plastic microparticles (on average, 1.

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Background: Due to the prolonged usage of Bt-based biopesticides and Bt-transgenic crops worldwide, insects are continually developing resistance against Cry toxins. This resistance may occur if any mechanistic step in the insecticidal process is disrupted possibly because of the alteration in Cry-receptor binding affinity due to mutation in receptor genes. Compared to other lepidopteran insects, Cry receptor-related research has made asymmetric progress in the model insect Galleria mellonella.

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The brain connectome maps the structural and functional connectivity that forms an important neurobiological basis for the analysis of human cognitive traits while the genetic predisposition and our cognition ability are frequently found in close association. The issue of how genetic architecture and brain connectome causally affect human behaviors remains unknown. To seek for the potential causal relationship, in this paper, we carried out the causal pathway analysis from single nucleotide polymorphism (SNP) data to four common human cognitive traits, mediated by the brain connectome.

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bacteria secrete a repertoire of protein toxins that can kill the host insect. Among them, toxin complex (Tc) proteins have gained significant attention due to their wider conservation across the different bacterial genera. In our laboratory, a C-terminal domain of TcaB protein was characterized from bacterium that conferred the potent oral insecticidal effect on .

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The present study was aimed to examine the antibacterial potential of essential oil (BNEO) against causal agent of bacterial wilt and Nitrosomonas sp., the nitrifying bacteria. In poisoned food assay, BNEO showed 100% growth inhibition of at ≥ 125 µg mL.

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Environmental concerns related to synthetic pesticides and the emphasis on the adoption of an integrated pest management concept as a cardinal principle have strengthened the focus of global research and development on botanical pesticides. A scientific understanding of the mode of action of biomolecules over a range of pests is key to the successful development of biopesticides. The present investigation focuses on the protein-ligand interactions of allyl isothiocyanate (AITC), a major constituent of black mustard ( essential oil (MEO) against two pests, namely, (Mi) and f.

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Aims: 1: Describe the epidemiology and determine risk factors for COVID-19 associated mucormycosis. 2: Elaborate the clinical spectrum of Rhino-Orbital-Cerebral Mucormycosis (ROCM), pattern of neuroaxis involvement and it's radiological correlates.

Methods: Observational study.

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Mitochondria form tubular networks that undergo coordinated cycles of fission and fusion. Emerging evidence suggests that a direct yet unresolved interaction of the mechanoenzymatic GTPase dynamin-related protein 1 (Drp1) with mitochondrial outer membrane-localized cardiolipin (CL), externalized under stress conditions including mitophagy, catalyzes essential mitochondrial hyperfragmentation. Here, using a comprehensive set of structural, biophysical, and cell biological tools, we have uncovered a CL-binding motif (CBM) conserved between the Drp1 variable domain (VD) and the unrelated ADP/ATP carrier (AAC/ANT) that intercalates into the membrane core to effect specific CL interactions.

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Root-knot nematode, Meloidogyne incognita is one of the most destructive nematodes worldwide. Essential oils (EOs) are being extensively utilized as eco-benign bionematicides, although the precise mechanism of action remains unclear. Pogostemon cablin Benth.

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Sorption of atrazine (ATZ), imidacloprid (IMIDA) and azoxystrobin (AZOXY) in single-, bi- and ternary-solutes system was modelled using phosphoric acid-treated rice straw biochar (T-RSBC). The T-RSBC showed stronger sorption capacity for IMIDA in single- and bi-solute systems. The Freundlich constant (K) in ternary system followed the order: ATZ (222.

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Intertidal microbial communities occur as biofilms or microphytobenthos (MPB) which are sediment-attached assemblages of bacteria, protozoa, fungi, algae, diatoms embedded in extracellular polymeric substances. Despite their global occurrence, they have not been reviewed in light of their structural and functional characteristics. This paper reviews the importance of such microbial communities and their importance in carbon dioxide sequestration as well as pollutant bioremediation.

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