Publications by authors named "Abhinav Vadassery"
Article Synopsis
- Kindling models are important animal models for studying epilepsy, characterized by the gradual progression from brief focal seizures to generalized tonic-clonic seizures through sub-threshold stimulation.
- These models utilize techniques like implanted electrodes and chemoconvulsants to induce seizures, allowing researchers to test new antiseizure medications with high predictive validity.
- The article offers detailed protocols for different kindling methods, along with insights into using pharmacological agents and genetically modified mice to better understand seizure dynamics and potential treatments for epilepsy.*
