Publications by authors named "Abhinav Sinha"

Background: Being judgmental about self-body image and satisfaction or dissatisfaction with one's own body is a natural phenomenon. If perceived incorrectly can lead to dissatisfaction and negative social, emotional, psychological and physical consequences.

Methods: A cross-sectional study was planned and the data was collected with the help of a semi-structured proforma.

View Article and Find Full Text PDF
Article Synopsis
  • India is experiencing an increase in non-communicable diseases (NCDs) among older adults, with a focus on understanding the relationship between disability and multimorbidity (having multiple chronic conditions).
  • Using data from a 2015 WHO survey, the study analyzed 7,118 participants aged 50 and above to evaluate disability levels and the prevalence of multimorbidity.
  • Findings indicated that 89% of participants had some form of disability, with 39.7% also experiencing multimorbidity, highlighting a significant association between the two issues in this demographic group.
View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated the effectiveness and tolerability of the antimalarial drug ganaplacide in combination with lumefantrine solid dispersion (LUM-SDF) for treating uncomplicated falciparum malaria across various age groups in a Phase II clinical trial.
  • The trial consisted of three parts: a run-in phase assessing pharmacokinetic interactions, a regimen comparison in adults and adolescents, and a dosage assessment in children aged 2 to under 12 years.
  • Results indicated that co-administration of ganaplacide and LUM-SDF did not significantly alter drug exposure levels, with both drugs showing adequate exposure for efficacy across different age and weight groups, despite some variability.
View Article and Find Full Text PDF
Article Synopsis
  • Multimorbidity is increasing in Nepal, but there's limited research, so this study aimed to review existing literature to estimate its prevalence and identify risk factors and consequences.
  • The researchers analyzed data from various medical databases, including a total of seven relevant studies, which showed a prevalence of multimorbidity ranging from 13.96% to 70.1%, with a pooled prevalence of 25.05%.
  • Key risk factors for multimorbidity included older age, living in urban areas, and lower levels of education, highlighting significant variability in study methods and prevalence rates.
View Article and Find Full Text PDF

In this article, we propose a new formation scheme for a leader-follower unmanned aerial vehicle (UAV) system inspired by a human pilot's behavior wherein the formation geometry does not necessarily remain fixed as the vehicles maneuver. In other words, the position and the orientation of the follower with respect to the leader are subject to change as they maneuver while satisfying some constraints. Our strategy ensures that the follower UAV maintains a desired fixed relative distance with respect to the leader UAV, whereas its orientation with respect to the leader UAV may change to reduce its control effort and provide it with a tactical advantage.

View Article and Find Full Text PDF

The constantly changing nature of cyber threats presents unprecedented difficulties for people, institutions, and governments across the globe. Cyber threats are a major concern in today's digital world like hacking, phishing, malware, and data breaches. These can compromise anyone's personal information and harm the organizations.

View Article and Find Full Text PDF

Background: Sulfadoxine-pyrimethamine (SP), as a partner to artesunate as ACT is the treatment of choice for uncomplicated P. falciparum infections in the majority of India and SP-resistance has a potential to lead to ACT failure. In the lack of robust surveillance of therapeutic efficacy of SP, validate molecular markers of SP-resistance offer a hint of failing SP.

View Article and Find Full Text PDF

With the decline in HIV mortality, a concomitant increase in morbidity and death not directly related to HIV has been witnessed. Consequently, many countries especially low- and middle-income countries (LMICs) are now facing the dual burden of HIV and non-communicable diseases (NCDs). 2.

View Article and Find Full Text PDF
Article Synopsis
  • This is the first systematic review and meta-analysis focusing on the prevalence, risk factors, and consequences of multimorbidity in India, analyzing various studies to gather comprehensive data.
  • The review included 35 relevant articles out of over 5400 identified, revealing a pooled prevalence of 20% for multimorbidity, primarily affecting healthcare usage and quality of life.
  • The findings highlight significant variations in multimorbidity across different age groups and regions, emphasizing the need for further research and interventions targeting vulnerable populations.
View Article and Find Full Text PDF

In order to replace conventional diesel, biodiesel from various feedstocks is being researched for diesel engines. This study explores novel biodiesel blends produced from unconventional resources such as mentha piperita (peppermint), pontederia crassipes (water hyacinth), tamarindus indica (tamarind), and trichosanthes cucumerina (snake gourd) to assess the outcomes of a diesel engine. The fuel samples are designated as MP20, PC20, TC20, and TI20, which consist of 80% biodiesel and 20% diesel.

View Article and Find Full Text PDF

Malaria has inflicted serious morbidity and mortality across the globe. The major brunt of the disease has been on African, South-East Asian and South American countries. Proportionally, malaria has attracted global research priorities and this is evident from the number of publications related to malaria from across the globe, irrespective of its endemicity.

View Article and Find Full Text PDF

The recent article by Harit et al. in Human Genomics reported a novel association of the C allele of rs479200 in the human EGLN1 gene with severe COVID-19 in Indian patients. The gene in context is an oxygen-sensor gene whose T allele has been reported to contribute to the inability to cope with hypoxia due to increased expression of the EGLN1 gene and therefore persons with TT genotype of EGLN1 rs479200 are more susceptible to severe manifestations of hypoxia.

View Article and Find Full Text PDF

Physicians' hold pivotal roles in improving non-communicable diseases (NCDs). Studies conducted in India revealed that physicians' feel unprepared to address NCDs risk reduction and provide counseling. We conducted a gap analysis using desk reviews to identify inclusion of NCD risk reduction in medical curricula, and a scoping review to assess knowledge, attitude, perception, and practice related to NCD risk reduction among the undergraduate medical students in India.

View Article and Find Full Text PDF

Background: Malaria elimination mandates early and accurate diagnosis of infection. Although malaria diagnosis is programmatically dependent on microscopy/RDTs, molecular diagnosis has much better diagnostic accuracy. Higher cost of molecular diagnoses is a recognized challenge for use at the point of care.

View Article and Find Full Text PDF

Introduction: Cataracts are the leading cause of blindness among older people, but they can be treated with corrective surgery. India boasts the oldest blindness control programme in the world. We aimed to assess the prevalence of cataract surgery, and we compared the determinants of undergoing cataract surgery and identified the unmet needs for cataract surgery among older adults in India.

View Article and Find Full Text PDF

Lymphatic filariasis (LF) is a significant public health issue in India. Despite 10-15 rounds of mass drug administration (MDA) in India, the global LF elimination target of 2030 appears challenging. To strengthen the program, community and provider perspectives on ways to bridge a gap in MDA are needed.

View Article and Find Full Text PDF

Lymphatic filariasis (LF) persists as a public health problem in India. Despite more than ten rounds of mass drug administration (MDA), LF continues to be endemic in the Dhenkanal district of Odisha. Hence, we assessed the coverage and compliance of the MDA program and explored the factors affecting it in the Dhenkanal district.

View Article and Find Full Text PDF
Article Synopsis
  • * Researchers compared the accuracy of a non-invasive haemoglobin test (EzeCheck) with a traditional blood test using a haematology analyzer, finding moderate agreement in results (kappa=0.4221).
  • * The findings support the use of non-invasive testing in schools and communities to identify anaemia, which can lead to early treatment and contribute to the 'Anaemia Mukt Bharat' initiative.
View Article and Find Full Text PDF

Poor air quality, especially in urban regions among low-and middle-income countries such as India poses a significant healthcare challenge. Amongst urban areas, metropolitan cities garner the utmost importance for air quality related policies and studies with limited studies from tier II cities which are thought to be relatively immune to air pollution. Hence, we aimed to identify the most frequent respiratory morbidities and explore its correlation with exposure to ambient PM2.

View Article and Find Full Text PDF

With the increasing integration of renewable energy sources and nonlinear loads in the grid, it is necessary to compute energy and power quality parameters for monitoring as well as analyzing the power consumption indices (PCI) and power quality indices (PQI). Smart meters (SMs) can monitor the PCI and PQI at the consumer end. SM necessitates the measurement of voltage and current, which can be further processed by an algorithm for estimating different parameters through signal processing and arithmetic operations.

View Article and Find Full Text PDF

Background: India is on track to eliminate malaria by 2030 but emerging resistance to first-line antimalarials is a recognised threat. Two instances of rapid development, spread, and natural selection of drug-resistant mutant parasites in India (chloroquine across the country and artesunate + sulfadoxine-pyrimethamine [AS+SP] in the northeastern states) translated into drug policy changes for Plasmodium falciparum malaria in 2010 and 2013, respectively. Considering these rapid changes in the SP drug resistance-conferring mutation profile of P.

View Article and Find Full Text PDF
Article Synopsis
  • India has a diverse healthcare system that includes complementary and alternative medicine (AYUSH), where patients with multiple chronic conditions prefer these holistic treatments, leading researchers to study multimorbidity rates in AYUSH clinics in Delhi.
  • A study of 943 patients revealed a prevalence of 39.4% for multimorbidity, with diabetes being the most common condition at 14.7%, and older adults, women, and middle-class individuals showing higher likelihoods of multimorbidity.
  • The findings indicate the need for targeted health communication to address the needs of vulnerable groups like older individuals and women attending AYUSH clinics.
View Article and Find Full Text PDF