Analyzing Effects of Sickle Cell Disease on Morphometric and Cranial Growth in Indian Population.

Background: Sickle cell disease is the most pervasive autosomal recessive hereditary blood diseases and is characterized by the presence of sickle hemoglobin (HbS), which in turn gives rise to pathophysiological consequences. This HbS reduces the agility of erythrocytes plummeting their ability to pass through small vascular channels, which in turn results in increased blood viscosity and congestion of vascular beds, causing ischemia, local infarction, and hemolysis.

Objectives: The current study was conducted to carry out the morphometric analysis in patients with sickle cell disease.