Publications by authors named "Abhinashi Singh Sodhi"

Article Synopsis
  • - Gene therapy has advanced significantly in targeting genetic diseases and cancers, utilizing approaches like nanotechnology and CRISPR/Cas9 for more effective treatments.
  • - Nanotechnology enhances gene therapy by offering targeted drug delivery and low toxicity, while CRISPR/Cas9 is recognized for its powerful genome editing capabilities and broader applications compared to traditional therapies.
  • - Despite its potential, gene therapy faces challenges regarding safety and effectiveness that need to be resolved before it can be widely used in clinical settings; ongoing research aims to overcome these hurdles and improve patient outcomes.
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Article Synopsis
  • Laccase is an enzyme found in various organisms like microbes, plants, and insects that breaks down phenols and aromatic amines and has strong potential in research and industry due to its ability to degrade lignin.
  • Its applications span multiple industries including food (for wine stabilization and phenolic detection), cosmetics, wastewater treatment, textile biobleaching, and biofuel production, making it an important green biocatalyst.
  • Innovative production methods, such as microbial co-culturing and enzyme immobilization with new materials, are being explored to enhance laccase's efficiency and stability, though challenges like high production costs and purification hurdles remain.
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The increasing demand for the development of sustainable strategies to utilize and process agro-industrial residues paves new paths for exploring innovative approaches in this area. Biotechnology based microbial transformations provide efficient, low cost and sustainable approaches for the production of value added products. The use of organic rich residues opens new avenues for the production of enzymes, pigments, biofuels, bioactive compounds, biopolymers etc.

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The oral microbiome is diverse in its composition due to continuous contact of oral cavity with the external environment. Temperatures, diet, pH, feeding habits are important factors that contribute in the establishment of oral microbiome. Both culture dependent and culture independent approaches have been employed in the analysis of oral microbiome.

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