Loading and release of doxorubicin hydrochloride from iron(iii) trimesate MOF and zinc oxide nanoparticle composites.

A significant amount of work has been done in recent years for the development of metal organic framework (MOF) based drug delivery vehicles. Often, nanomaterials such as iron oxide (Fe3O4), zinc oxide (ZnO), and other metal oxides like graphene oxide etc. are incorporated into the structures to impart additional functionality.

Calcium channel TRPV6 expression in human duodenum: different relationships to the vitamin D system and aging in men and women.

Unlabelled: Intestinal absorption of calcium affects bone mineralization and varies greatly. In human duodenum, expression of the calcium channel TRPV6 was directly related to blood 1,25-dihydroxyvitamin D in men, but effects of age with lower median vitamin D receptor levels were more significant in women.

Introduction: The TRPV6 calcium channel/transporter is implicated in animal studies of intestinal calcium absorption, but in humans, its role and relationship to differences in mineral metabolism is unclear.