Endoplasmic Reticulum-Targeting Delayed Fluorescent Probe for Dual-mode Nitroreductase Sensing.

Organic thermally activated delayed fluorescence (TADF) materials, known for their long-lived emission properties, are highly sought after for background-free imaging of selective analytes in time-resolved modes. However, their practical application faces significant challenges, including the air sensitivity of triplet states, lack of organelle specificity, and the absence of precise analyte recognition centres. These limitations hinder their effectiveness in detecting key cancer biomarkers such as nitroreductase (NTR).

Controlled Photooxidation via Singlet Oxygen Generation by Triplet Harvesting in a Heavy Atom Free Pure Organic Dithienylethene-Naphthalene Diimide.

Noninvasive control over the reversible generation of singlet oxygen (O) has found the enormous practical implications in the field of biomedical science. However, metal-free pure organic emitters, connected with a photoswitch, capable of generating "on-demand" O via triplet harvesting remain exceedingly rare; therefore, the utilization of these organic materials for the reversible control of singlet oxygen production remains at its infancy. Herein, an ambient triplet mediated emission in quinoline-dithienylethene (DTE)-core-substituted naphthalene diimide (cNDI) derivative is unveiled via delayed fluorescence.

Unraveling Early-Stage Dynamics of Cage-to-Covalent Organic Framework Transformation at Liquid-Liquid Interface.

Postsynthetic linker exchange (PLE) has emerged as an emerging synthetic strategy for constructing high-quality covalent organic frameworks (COFs) from preassembled entities such as linear polymers, amorphous networks, COFs, and porous organic cages by using the principles of dynamic covalent chemistry. The PLE strategy has recently been extended at the liquid-liquid interface to fabricate highly crystalline two-dimensional (2D)-COF membranes at a faster time scale (24 h). Examining the early stages of the interfacial PLE dynamics becomes essential to understanding the expedited COF growth process.

Surface functionalized perovskite nanocrystals: a design strategy for organelle-specific fluorescence lifetime multiplexing.

Fluorescent molecules or materials with high photoluminescence quantum yields and stability towards photobleaching are ideally suited for multiplex imaging. Despite complying with such properties, perovskite nanocrystals (Pv-NCs) are rarely used for bioimaging owing to their toxicity and limited stability in aqueous media and towards human physiology. We aim to address these deficiencies by designing core-shell structures with Pv-NCs as the core and surface-engineered silica as the shell (SiO@Pv-NCs) since silica is recognized as a biologically benign carrier material and is known to be excreted through urine.

Imidazolium and Pyridinium-Based Ionic Porous Organic Polymers: Advances in Transformative Solutions for Oxoanion Sequestration and Non-Redox CO Fixation.

The rapid pace of industrialization has led to a multitude of detrimental environmental consequences, including water pollution and global warming. Consequently, there is an urgent need to devise appropriate materials to address these challenges. Ionic porous organic polymers (iPOPs) have emerged as promising materials for oxoanion sequestration and non-redox CO fixation.

Copper/Zinc-Catalyzed Stitching of 2-Carbonylanilines with Bis(ynamides): Access to Pyrrolo[2,3-]quinolines and Its Photophysical Studies.

Herein, a one-pot desulfonylative protocol enabled by copper(II)/zinc(II) salts to access pyrrolo[2,3-]quinolines in good to excellent yields from 2-carbonylanilines and ynamide-derived buta-1,3-diynes has been reported. Significantly, various 2-carbonylanilines carrying reactive functional groups are well tolerated. Moreover, a gram-scale synthesis and synthetic application highlight the practical utility of the current protocol.

A porous organic polymer for symmetric sodium dual-ion batteries through an adsorption-intercalation-insertion mechanism.

A porous organic polymer (POP) has been developed for dual-ion storage in all organic symmetric rechargeable batteries. The triphenylamine-pyrene-based POP could host sodium and hexafluorophosphate ions acting as the anode and the cathode, respectively, through the adsorption-intercalation and insertion mechanism. The current study highlights the concept of widening the potential window of a dual ion battery by judicious selection of the constituent moieties.

Unveiling autophagy and aging through time-resolved imaging of lysosomal polarity with a delayed fluorescent emitter.

Detecting the lysosomal microenvironmental changes like viscosity, pH, and polarity during their dynamic interorganelle interactions remains an intriguing area that facilitates the elucidation of cellular homeostasis. The subtle variation of physiological conditions can be assessed by deciphering the lysosomal microenvironments during lysosome-organelle interactions, closely related to autophagic pathways leading to various cellular disorders. Herein, we shed light on the dynamic lysosomal polarity in live cells and a multicellular model organism, (), through time-resolved imaging employing a thermally activated delayed fluorescent probe, DC-Lyso.

Boosting Photocatalytic Nitrogen Fixation via Nanoarchitectonics Using Oxygen Vacancy Regulation in W-Doped BiMoO Nanosheets.

Ammonia and nitrates are key raw materials for various chemical and pharmaceutical industries. The conventional methods like Haber-Bosch and Ostwald methods used in the synthesis of ammonia and nitrates, respectively, result in harmful emission of gases. In recent years, the photocatalytic fixation of N into NH and nitrates has become a hot topic since it is a green and cost-effective approach.

Structural Modulation of Nitrogen-Rich Covalent Organic Frameworks for Iodine Capture.

Developing efficient adsorbent materials for iodine scavenging is essential to mitigate the threat of radioactive iodine causing adverse effects on human health and the environment. In this context, we explored N-rich two-dimensional covalent organic frameworks (COFs) with diverse functionalities for iodine capture. The pyridyl-hydroxyl-functionalized triazine-based novel 5,5',5″-(1,3,5-triazine-2,4,6-triyl)tris(pyridine-2-amine) (TTPA)-COF possesses high crystallinity (crystalline domain size: 24.

UV-to-NIR Harvesting Conjugated Porous Polymer Nanocomposite: Upconversion and Plasmon Expedited Thioether Photooxidation.

Photocatalysts capable of harvesting a broad range of the solar spectrum are essential for sustainable chemical transformations and environmental remediation. Herein, we have integrated NIR-absorbing upconversion nanoparticles (UCNP) with UV-Vis absorbing conjugated porous organic polymer (POP) through the in situ multicomponent C-C coupling to fabricate a UC-POP nanocomposite. The light-harvesting ability of UC-POP is further augmented by loading plasmonic gold nanoparticles (AuNP) into UC-POP.

Unveiling the Long-Lived Emission of Copper Nanoclusters Embedded in a Protein Scaffold.

Protein-conjugated coinage metal nanoclusters have become promising materials for optoelectronics and biomedical applications. However, the origin of the photoluminescence, especially the long-lived excited state emission in these metal nanoclusters, is still elusive. Here, we unveiled the underlying mechanism of long-lived emission in albumin protein-conjugated copper nanoclusters (Cu NCs) using steady state and time-resolved spectroscopic techniques.

Tailoring defects in SrTiO by one step nanoarchitectonics for realizing photocatalytic nitrogen fixation in pure water.

Surface contamination of materials by nitrogenous impurities is a major problem that can bias the quantification of ammonia in photocatalytic N fixation reactions. In this work, SrTiO nanocubes were prepared by using a nitrogenous precursor and engineered with Ti sites and oxygen vacancy defects in a one-step solvothermal approach. It was observed that the synthesized materials were containing surface nitrogenous impurities and therefore a rigorous cleaning procedure was adopted to eliminate them to the best extent.

Fluorescence correlation spectroscopy and fluorescence lifetime imaging microscopy for deciphering the morphological evolution of supramolecular self-assembly.

The properties and functions of non-covalent interaction-driven fluorescent supramolecular self-assembly depend greatly on their evolution dynamics. Electron microscopy, atomic force microscopy, and confocal laser scanning microscopy have been used to elucidate the formation of molecular self-assembly. However, some pertinent issues, such as the drying or freezing of the sample for electron microscopy, the influence of the interactions between the tip and the sample in atomic force microscopy imaging, and the low spatial resolution of confocal laser scanning microscopy images, often impede the real-time analysis and exploration of the dynamics of molecular self-assembly processes.

Pyridinium-Functionalized Ionic Porous Organic Polymer for Rapid Scavenging of Oxoanions from Water.

Metal oxoanions adversely affect the food chain through bioaccumulation and biomagnification. Therefore, they are among the major freshwater contaminants that require immediate remediation. Although several adsorbents are developed over the years for sequestering these micropollutants, the selective removal of oxoanions remains still a formidable challenge.

Transformation of an Imine Cage to a Covalent Organic Framework Film at the Liquid-Liquid Interface.

Dynamic covalent chemistry (DCC) opens up a fascinating route for the construction of well-organized supramolecular architectures, starting from organic molecular cages to crystalline macromolecular covalent organic frameworks (COFs). Herein, for the first time, we have manifested a facile room-temperature DCC-directed transformation of discrete organic imine cage-to-COF film at the liquid-liquid interface. The unfolding of the cage leading to the generation of imine intermediates, followed by their interface-assisted preorganization and subsequent growth of the COF film, are elucidated through detailed spectroscopic and microscopic investigations.

,'-octyl biphenothiazine and dibenzothiophene dioxide-based soluble porous organic polymer for biphasic photocatalytic hydrogen evolution.

A donor-acceptor-based soluble porous organic polymer (PzDBS) was fabricated using a flexible core composed of ,'-octyl biphenothiazine and a rigid building unit involving dibenzothiophene dioxide. The soluble porous organic polymer was explored for aqueous-organic biphasic photocatalytic hydrogen evolution, introducing a promising avenue in the domain of porous polymer photocatalysts.

Molecular to Supramolecular Self-Assembled Luminogens for Tracking the Intracellular Organelle Dynamics.

Deciphering the dynamics of intracellular organelles has gained immense attention due to their subtle control over diverse, complex biological processes such as cellular metabolism, energy homeostasis, and autophagy. In this context, molecular materials, including small-organic fluorescent probes and their supramolecular self-assembled nano-/microarchitectures, have been employed to explore the diverse intracellular biological events. However, only a handful of fluorescent probes and self-assembled emissive structures have been successfully used to track different organelle's movements, circumventing the issues related to water solubility and long-term photostability.

Porous Organic Polymers: Promising Testbed for Heterogeneous Reactive Oxygen Species Mediated Photocatalysis and Nonredox CO Fixation.

Catalysts play a pivotal role in achieving the global need for food and energy. In this context, porous organic polymers (POPs) with high surface area, robust architecture, tunable pore size, and chemical functionalities have emerged as promising testbeds for heterogeneous catalysis. Amorphous POPs having functionalized interconnected hierarchical porous structures activate a diverse range of substrates through covalent/non-covalent interactions or act as a host matrix to encapsulate catalytically active metal centers.

Nanostructured Hypercrosslinked Porous Organic Polymers: Morphological Evolution and Rapid Separation of Polar Organic Micropollutants.

Nanostructured hypercrosslinked porous organic polymers have triggered immense research interest for a broad spectrum of applications ranging from catalysis to molecular separation. However, it still remains a challenge to tune their nanoscale morphology. Herein, we demonstrated a remarkable variation of morphologies of triptycene-based hypercrosslinked microporous polymers starting from irregular aggregates (FCTP) to rigid spheres (SCTP) to two-dimensional nanosheets (SKTP) from three distinct polymerization methodologies, Friedel-Crafts knitting using an external crosslinker, Scholl reaction, and solvent knitting, respectively.

Three in One: Stimuli-Responsive Fluorescence, Solid-State Emission, and Dual-Organelle Imaging Using a Pyrene-Benzophenone Derivative.

Small organic luminogens, owing to their contrasting stimuli-responsive fluorescence in solution along with strong emission in aggregated and solidstates, have been employed in optoelectronic devices, sensors, and bioimaging. Pyrene derivatives usually exhibit strong fluorescence and concentration-dependent excimer/aggregate emission in solution. However, the impacts of microenvironments on the monomer and aggregate emission bands and their relative intensities in solution, solid, and supramolecular aggregates are intriguing.

UV to NIR multistate electrochromism and electrofluorochromism in dibenzophenazine-arylamine derivatives.

An intriguing case of intramolecular and intervalence charge transfer-driven multistate electrochromism and electrofluorochromism in dibenzophenazin-(phenyl)methanone and arylamine-based redox-active donor-acceptor-donor molecules was elucidated. Tunable absorption from UV to NIR and on-off switching of fluorescence in a single-component all-organic molecular material by a subtle variation of electric potentials were demonstrated.

Two-dimensional Covalent Organic Frameworks for Electrochromic Switching.

The electrochromic materials have received immense attention for the fabrication of smart optoelectronic devices. The alteration of the redox states of the electroactive functionalities results in the color change in response to electrochemical potential. Even though transition metal oxides, redox-active small organic molecules, conducting polymers, and metallopolymers are known for electrochromism, advanced materials demonstrating multicolor switching with fast response time and high durability are of increasing demand.