Seventeen year old boy, a case of relapsed acute lymphoblastic leukemia 10 years post allogeneic transplantation, presented to us with acute onset of right hemiparesis. The imaging revealed contrast enhancing lesion in the frontal lobe, biopsy of the same was consistent with glioblastoma multiforme (GBM). He had received total body irradiation (TBI) based conditioning regimen prior to transplant.
View Article and Find Full Text PDFWe report here a case of 52-year-old male presenting with penile ulcer. On evaluation, he was diagnosed to have Carcinoma penis with concurrent CML in chronic phase. Clinical examination showed pallor, bilateral inguinal lymphadenopathy, bilateral pitting pedal oedema and hepatosplenomegaly.
View Article and Find Full Text PDFIndian J Hematol Blood Transfus
September 2014
Definition and diagnostic criteria for histiocytic sarcoma (HS) have changed over last two decades due to available new immunohistochemical markers, as well as better understanding of the biology of disease. We report here a case of 4 years old boy diagnosed as acute lymphoblastic leukemia (ALL), who later developed HS of pleura, when he was on maintenance phase of ALL protocol. HS constitutes less than 1 % of the haematolymphoid neoplasm, even more rare is association of HS with ALL.
View Article and Find Full Text PDFGranulocytic sarcoma occurs most commonly in acute myelogenous leukemia. The appearance of granulocytic sarcoma in chronic myelogenous leukemia signals accelerated phase/ blast transformation. This is a rare case of undiagnosed chronic myelogenous leukemia with granulocytic sarcoma causing cord compression, which went into tumour lysis syndrome requiring dialysis after starting of steroids and radiotherapy.
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