Publications by authors named "Abhay S Nigam"

Article Synopsis
  • Hemophagocytic Lymphohistiocytosis (HLH) is a rare but severe inflammatory syndrome caused by an overactive immune response, making its early diagnosis challenging due to non-specific symptoms.
  • This study analyzed twelve cases of HLH diagnosed from January 2015 to June 2018, reviewing clinical indications, laboratory tests, and bone marrow findings.
  • The findings aim to enhance understanding and improve early detection of HLH, facilitating prompt medical intervention for this life-threatening condition.
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Light chain myeloma (LCM) is an unusual neoplasm accounting for about 1 8% of all plasma cell myelomas. It is characterized by the absence of a detectable M protein in the serum and urine protein electrophoresis, altered free light chain ratio, bone marrow plasmacytosis and related organ or tissue damage. We report a 60-year-old man with LCM presenting with pancytopenia.

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Splenic Marginal Zone Lymphoma (SMZL) is a rare B-cell neoplasm comprising less than 2% of non-Hodgkin lymphomas. We hereby report a case of SMZL in a 66-year-old female who presented with fever and massive splenomegaly. Peripheral blood smear examination showed atypical lymphoid cells showing variable cytoplasmic processes.

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Acute Leukemia is one of the common haematological malignancies encountered with varied clinical and haematological presentation. In acute leukaemia, complications like bleeding and infection cause significant morbidity and mortality, thus overshadowing the thromboembolic events. Among the various malignant haematological disorders, the association of thromboembolic events is often noted with acute promyelocytic leukemia, though the overall frequency of such events remains very low.

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