Publications by authors named "Abesig Julius"
Objective: To assess the methodological quality of individual participant data (IPD) meta-analysis and to identify areas for improvement.
Design: Systematic review.
Data Sources: Medline, Embase, and Cochrane Database of Systematic Reviews.
The aim of this study was to explore the impact of polymorphism of PD-1 gene and its interaction with tea drinking on susceptibility to tuberculosis (TB). A total of 503 patients with TB and 494 controls were enrolled in this case-control study. Three single-nucleotide polymorphisms of PD-1 (rs7568402, rs2227982 and rs36084323) were genotyped and unconditional logistic regression analysis was used to identify the association between PD-1 polymorphism and TB, while marginal structural linear odds models were used to estimate the interactions.
View Article and Find Full Text PDFImpact of gene polymorphisms and gene-tea interaction on susceptibility to tuberculosis.
World J Clin Cases
October 2020
Article Synopsis
- This study investigated the relationship between specific genetic variations (SNPs) in the gene associated with the PI3K/Akt/mTOR signaling pathway and the risk of tuberculosis (TB) within the Han population of China, particularly focusing on how these variations interact with tea drinking habits.
- Researchers analyzed data from 503 TB patients and 494 healthy controls, examining five SNPs to assess their connection to TB susceptibility and used statistical models to assess the impact of tea consumption.
- The findings revealed that four of the SNPs were significantly associated with increased TB risk, suggesting that genetic factors and tea drinking may influence susceptibility to the disease.
Background: Exclusive breastfeeding (EBF) is recommended for the first six months of age by the World Health Organization. Mothers' good knowledge and positive attitude play key roles in the process of exclusive breastfeeding practices. In this study, we report on a systematic review of the literature that aimed to examine the status of mothers' knowledge, attitude, and practices related to exclusive breastfeeding in East Africa, so as to provide clues on what can be done to improve exclusive breastfeeding.
View Article and Find Full Text PDFChronic hepatitis B (HBV) remains a significant public health problem in Ghana and past reviews conducted could not calculate a nationwide prevalence of the disease due to lack of primary research for some regions of the country. We therefore conducted this study to summarize and update the available information on HBV infection burden (prevalence) in Ghana from 2015-2019.We systematically searched PubMed, Embase, ScienceDirect, and Google Scholar to retrieve primary studies published in peer-reviewed journals from November 2015 to September 2019, assessing the prevalence of HBV among the Ghanaian populace.
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