Publications by authors named "Abera Hadgu"
Congenital malformations are defects of the morphogenesis of organs or body during the pregnancy period and are identifiable at pre- or postnatal. They are identified as the major cause of child mortality worldwide. There is a need to understand the prevalence of congenital malformations in Tigray and Ethiopia in general as surveillance data are lacking.
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- Intramuscular benzathine penicillin G (BPG) injections are essential for preventing acute rheumatic fever and rheumatic heart disease, but there are uncertainties regarding how effective they are across different ethnic groups and preparations.
- A study in Ethiopia analyzed the pharmacokinetics (PK) of BPG in ARF/RHD patients by collecting serum samples after injections and assessing them using advanced assay techniques.
- Results showed that Ethiopian patients had lower drug distribution and longer absorption half-life compared to Indigenous Australians, with most not maintaining effective drug levels for the necessary duration, indicating a need for improved BPG strategies in treatment programs.
Objective: The objective of this study was to ascertain the effects of high-intensity chronic endurance training on cardiovascular markers of active populations and athletes.
Methods: This review was conducted in accordance with the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. We used databases of PubMed, Science Direct, SPORTDiscus, Google Scholar and grey literatures with Mesh and free-text search as well as manual searches to identify relevant studies from June 2017 to September 2019.
Article Synopsis
- Previous research suggests that patients of African ancestry may not respond as well to certain hypertension medications, leading to continued use of these without solid evidence in Ethiopia.
- This study compared the effectiveness of three antihypertensive drugs (nifedipine, enalapril, and hydrochlorothiazide) on blood pressure reduction in Ethiopian patients from November 2016 to April 2017, using a randomized method.
- Results showed that nifedipine significantly reduced systolic blood pressure more than the other drugs, but there was no significant difference in diastolic blood pressure effects among the groups.