Does discontinuation of desflurane at the time of neostigmine administration speed recovery from cisatracurium block compared to that with a propofol-based technique?

Background: Volatile anaesthetics are known to influence the effect of neostigmine as an antagonist of neuromuscular block. The aim of the present study was to investigate whether discontinuation of desflurane at the time of neostigmine administration shortens reversal time from cisatracurium block, compared to that with a propofol-based anaesthesia.

Methods: Ten volunteers were studied twice.

Effect of renal failure and cirrhosis on the pharmacokinetics and neuromuscular effects of rapacuronium administered by bolus followed by infusion.

Background: Recent trials indicate that rapacuronium's pharmacokinetic characteristics are influenced by both renal failure and cirrhosis but the time course of a single bolus dose of 1.5 mg/kg is affected minimally. The authors reassessed these pharmacokinetic findings and examined the time course of the same bolus dose followed by a 30-min infusion.

Effects of Ca2+ channel antagonists and benzodiazepine receptor ligands in normal and skinned rat urinary bladder.

The effects of Ca2+ channel antagonists and benzodiazepine receptor ligands against concentration-dependent contractions of rat urinary bladder induced by CaCl2 (0.1-50 mM, in K(+)-depolarized tissues), KCl (1-100 mM) and acetylcholine (0.1 microM to 1 mM) were studied.

[Effects of midazolam on the delivery and consumption of myocardial oxygen in the postoperative period of children undergoing heart surgery].

Introduction: The aim of this study was to evaluate the effect of midazolam on the variables which determine myocardial oxygen delivery and consumption relationship (endocardiac viability index) in children undergoing cardiac surgery under extracorporal circulation.

Methods: The study was carried out in 15 children to whom a doses of midazolam of 0.2 mg/kg was given in immediate postoperative period upon hemodynamic stabilization.

[Application of continuous positive pressure to the uppermost lung in patients ventilated through a single lung].

We have studied the oxygenation process in a series of 20 patients who underwent thoracic surgery and were ventilated through a single lung. There were 19 men and one woman with a mean age (+/- SD) of 63 +/- 10.5 years, a mean height of 166 +/- 37.

[Prevalence of HIV antibody carriers in patients assisted in the recovery room].

A study has been performed on 200 patients at the Recovery Department of our hospital during 1987. This study was carried out in order to determine patients with human immunodeficiency virus (HIV) antibody. This group was randomized and consisted of 154 men and 46 women, with an average age of 35.