Effectiveness and safety of ertapenem used in hospital-at-home units: data from Spanish Outpatient Parenteral Antimicrobial Therapy Registry.

Aim: To evaluate the effectiveness and safety of ertapenem in patients hospitalized at home.

Patients & Methods: Retrospective analysis of data from Spanish Outpatient Parenteral Antimicrobial Therapy (OPAT) registry.

Results: Data from 1428 patients (median age 70 years; 5.

Safety and effectiveness of outpatient parenteral antimicrobial therapy in older people.

Objectives: We analyse the safety and effectiveness of self-outpatient parenteral antimicrobial therapy (s-OPAT) in older patients.

Methods: We prospectively evaluated all adults admitted to our home hospitalization unit (HHU) for s-OPAT in the period 2008-12 in whom the bacteria responsible for the infection were identified. We divided patients into three age groups: <65, 65-79 and ≥80 years.

Supervised versus non-supervised exercise in patients with recent myocardial infarction: A propensity analysis.

Background: The influence of supervised versus non-supervised exercise training on outcome in patients with a recent myocardial infarction (MI) is controversial.

Design: Longitudinal observational study.

Methods: FRENA is an ongoing registry of stable outpatients with symptomatic coronary, cerebrovascular or peripheral artery disease.

Cilostazol and outcome in outpatients with peripheral artery disease.

Background: Cilostazol increases the walking distance in patients with intermittent claudication, but there is scarce evidence of any effect on the risk for subsequent ischemic events, bleeding or death.

Patients And Methods: We used data from the FRENA Registry to compare the clinical outcome in stable outpatients with intermittent claudication, according to the use of cilostazol.

Results: As of January 2013, 1,317 patients with intermittent claudication were recruited in FRENA, of whom 191 (14.

[Consensus guidelines for the management of community acquired pneumonia in the elderly patient].

The incidence of community-acquired pneumonia increases with age and is associated with an elevated morbidity and mortality due to the physiological changes associated with aging and a greater presence of chronic disease. Taking into account the importance of this disease from an epidemiological and prognostic point of view, and the enormous heterogeneity described in the clinical management of the elderly, we believe a specific consensus document regarding this patient profile is necessary. The purpose of the present work was to perform a review of the evidence related to the risk factors for the etiology, the clinical presentation, the management and the treatment of community-acquired pneumonia in elderly patients with the aim of producing a series of specific recommendations based on critical analysis of the literature.

Cardiac rehabilitation and outcome in stable outpatients with recent myocardial infarction.

Objective: To compare the mortality rate and the rate of subsequent ischemic events (myocardial infarction [MI], ischemic stroke, or limb amputation) in patients with recent MI according to the use of cardiac rehabilitation or no rehabilitation.

Design: Longitudinal observational study.

Setting: Ongoing registry of outpatients.