In Vitro Evaluation of α-amylase and α-glucosidase Inhibition of 2,3-Epoxyprocyanidin C1 and Other Constituents from Poir.

Diabetes mellitus is a metabolic disorder which is one of the leading causes of mortality and morbidities in elderly humans. Chronic diabetes can lead to kidney failure, blindness, limb amputation, heart attack and stroke. Physical activity, healthy diets and medications can reduce the incidence of diabetes, so the search for more efficient antidiabetic therapies, most especially from natural products, is a necessity.

Two new flavones glycosides with antimicrobial activities from Gürke (Lamiaceae).

Gürke from the Lamiaceae family is a Cameroonian medicinal plant. The crude methanol, methanol residual and ethyl acetate extracts of leaves have been phytochemically studied using chromatography column to afford four compounds; two new flavones glycoside: clerodendronone 1a () and clerodendronone 1b () along with two known compounds: 5,7-dihydroxy-4'-methoxyflavone () and 5-hydroxy-7,4'-dimethoxyflavone (). Compound structures have been elucidated on the basis of their spectroscopy data and with literature information.

Excelsanone, a new isoflavonoid from (Fabaceae), with antioxidant and cytotoxic effects on prostate cancer cells lines.

A new isoflavonoid, excelsanone (), was isolated from the ethyl acetate extract of stem bark, together with three known compounds namely 6,8-diprenylgenistein (), β-sitosterol () and sitosteryl--D-glucopyranoside (). Their structures were elucidated using spectroscopic methods (HR-ESI-MS, NMR and IR) and by comparison with some literature data. The antioxidant activity of crude extracts and two isolated compounds was evaluated using free radical scavenging (DPPH) and Ferric Reducing Ability Power (FRAP) methods with catechin as standard.