Cigarette Smoke Constituents and Nicotine Differentially Affect Cytokine Production by Human Macrophages Stimulated by TLR Ligands : Considerations for a Standardised Protocol.

Chronic obstructive pulmonary disease (COPD) is an inflammatory lung condition associated with cigarette (tobacco) smoking. Numerous animal studies have been conducted to investigate the links between cigarette smoke, nicotine and infection in lung pathology. As an alternative to animal experiments, we used an system to investigate the effects of cigarette smoke extract (CSE) or nicotine on TNF-α and IL-10 production by monocyte-derived human macrophages.

Versatility of copper-iron bimetallic nanoparticles fabricated using Hibiscus rosa-sinensis flower phytochemicals: various enzymes inhibition, antibiofilm effect, chromium reduction and dyes removal.

Bimetallic nanoparticles (NPs) are considered superior in terms of stability and function with respect to its monometallic counterparts. Hence, in the present study Hibiscus rosa-sinensis flower extract was used to synthesis copper-iron bimetallic nanoparticles (HF-FCNPs). HF-FCNPs was characterized and its applications (biological and environmental) were determined.

Modulating oxidative stress, apoptosis, and mitochondrial dysfunctions on cardiotoxicity induced by aluminum phosphide pesticide using resveratrol.

The agricultural fumigant pesticide aluminum phosphide (AlP) is cardiotoxic. Water causes AlP to emit phosphine gas, a cardiac toxin that affects heart function and causes cardiogenic shock. AlP poisoning's high fatality rate is due to cardiotoxicity.

Phytochemical Screening of L. as a Potential Anticholinesterase and Antioxidant-Medicinal Plant for Cognitive Decline Disorders.

The inhibition of acetylcholinesterase (AChE) by cholinergic agents has been promoted as a potent strategy for treating and managing cognitive decline disorders. A wide range of natural products has long been used as potential sources or formulations of cholinergic inhibitors. Therefore, this study aimed to evaluate different L.