Publications by authors named "Abeer Qush"
The diet-microbiome-immunity axis is one among the many arms that draw up the "we are what we intake" proclamation. As such, studies on the effect of food and beverage intake on the gut environment and microbiome and on modulating immunological responses and the host's susceptibility to pathogens are on the rise. A typical accompaniment in different sustenance we consume on daily basis is the trimethylxanthine alkaloid caffeine.
View Article and Find Full Text PDFOn quotidian basis, living beings work out an armistice with their microbial flora and a scuffle with invading pathogens to maintain a normal state of health. Although producing virulence factors and escaping the host's immune machinery are the paramount tools used by pathogens in their "arm race" against the host; here, we provide insight into another facet of pathogenic embitterment by presenting evidence of the ability of enteric pathogens to exhibit pathogenicity through modulating metabolic homeostasis in Drosophila melanogaster. We report that Escherichia coli and Shigella sonnei orally infected flies exhibit lipid droplet deprivation from the fat body, irregular accumulation of lipid droplets in the midgut, and significant elevation of systemic glucose and triglyceride levels.
View Article and Find Full Text PDFAs of March 2020, the time when the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became a pandemic, our existence has been threatened and the lives of millions have been claimed. With this ongoing global issue, vaccines are considered of paramount importance in curtailing the outbreak and probably a prime gamble to bring us back to 'ordinary life'. To date, more than 200 vaccine candidates have been produced, many of which were approved by the Food and Drug Administration (FDA) for emergency use, with the research and discovery phase of their production process passed over.
View Article and Find Full Text PDFArticle Synopsis
- SARS-CoV-2, the virus causing COVID-19, emerged as a global pandemic in March 2020, leading to a significant health crisis and loss of life worldwide.
- In response, over 200 vaccine candidates were developed quickly, with many receiving FDA emergency use authorization to combat the virus.
- The review discusses the various vaccine development platforms, their advantages and disadvantages, along with ongoing concerns regarding safety, efficacy, and the impact of new virus variants.
Aims: T2DM reach epidemic levels in the Arab countries. In this study, we aimed to perform a systematic review and meta-analysis to underline the susceptibility genetic profile of Arab patients with T2DM that result from SNPs.
Methods: We searched four literature databases (PubMed, Scopus, Science Direct and Web of Science) through January 2019.