Publications by authors named "Abeer A Rushdy"
Objectives: To study the potential factors include gene mutation, efflux pump and alteration of permeability associated with quinolone-resistance of Salmonella enterica strains isolated from patients with acute gastroenteritis and to evaluate the degree of synergistic activity of efflux pump inhibitors when combined with ciprofloxacin against resistant isolates.
Methods: Antimicrobial resistance patterns of fifty-eight Salmonella isolates were tested. Five isolates were selected to study the mechanism of resistance associated with quinolone group, including mutation in topoisomerase-encoding gene, altered cell permeability, and expression of an active efflux system.
Article Synopsis
- Developed two molecular techniques to quickly and specifically detect bacterial pathogens (E. coli, P. aeruginosa, and Salmonella spp.) in water samples.
- Optimized a multiplex-PCR assay using specific primer pairs for each pathogen, allowing for simultaneous detection.
- Achieved results indicating that the M-PCR assay significantly outperforms traditional methods, providing accurate results within 5 hours from sampling.