Water, sanitation, and hygiene in selected health facilities in Ethiopia: risks for healthcare acquired antimicrobial-resistant infections.

Background: Inadequate water, sanitation and hygiene (WASH) in health facilities, and the low adherence to infection control protocols can increase the risk of hospital-acquired (nosocomial) infections (HAIs). The risk for HAIs can increase morbidity, and mortality, health care cost, but also contribute to increased microbial resistance.

Objectives: The study aimed to assess WASH facilities and practices, and levels of nosocomial pathogens in selected health facilities in Oromia Region and Southern, Nations and Nationalities and Peoples (SNNPs) Region.

Antimicrobial resistance trends in clinical and in Ethiopia.

Background: Clinicians rely on local antimicrobial resistance pattern data to guide empiric treatment for seriously ill patients when culture and antimicrobial susceptibility testing results are not immediately available.

Objective: This study aimed to analyse 5-year trends in antimicrobial resistance profiles of and isolates.

Methods: Bacteriology reports from 2017 to 2021 at the Ethiopian Public Health Institute were analysed retrospectively.

Antimicrobial resistance profiles of bacterial isolates from clinical specimens referred to Ethiopian Public Health Institute: analysis of 5-year data.

Background: Antimicrobial resistance is one of the common global public health problems. The emergence of antimicrobial resistance is multifactorial, and tackling its development is challenging. Consequently, infections caused by resistant bacteria are unresponsive to conventional drugs, resulting in prolonged and severe illnesses, higher mortality rates, and considerable healthcare costs.

Antimicrobial Resistance Patterns of and Species at the Ethiopian Public Health Institute, Ethiopia: A Five-Year Retrospective Analysis.

Purpose: The study aimed to investigate the antimicrobial resistance patterns of and species isolated from clinical specimens over a period of five years, including resistance to methicillin and vancomycin.

Patients And Methods: Bacterial identification and antimicrobial susceptibility testing reports from 2017 to 2021 at the Ethiopian Public Health Institute were used for this retrospective study. The organisms were identified using either BD Phoenix M50, Vitek 2 compact, or conventional biochemical methods, whichever was available at the time of testing.

Characterization of plasmids carrying bla genes among extra-intestinal Escherichia coli clinical isolates in Ethiopia.

CTX-Ms are encoded by bla genes and are widely distributed extended-spectrum β-lactamases (ESBLs). They are the most important antimicrobial resistance (AMR) mechanism to β-lactam antibiotics in the Enterobacteriaceae. However, the role of transmissible AMR plasmids in the dissemination of bla genes has scarcely been studied in Africa where the burden of AMR is high and rapidly spreading.

Prevalence and Trends of Carbapenem-Resistant and Species Isolated from Clinical Specimens at the Ethiopian Public Health Institute, Addis Ababa, Ethiopia: A Retrospective Analysis.

Purpose: Carbapenem-resistant species and are the leading cause of nosocomial infections. Therefore, the objective of this study was to analyze the prevalence, antimicrobial susceptibility profile, and trends of carbapenem-resistant and species isolated from clinical specimens.

Patients And Methods: This retrospective study included data from Ethiopian Public Health Institute from 2017 to 2021.

Bacterial and fungal profile, drug resistance pattern and associated factors of isolates recovered from blood samples of patients referred to Ethiopian Public Health Institute: cross-sectional study.

Background: Blood stream infections are serious infections that usually induce prolongation of hospital stay, morbidity and mortality in several countries including Ethiopia. The aim of this study was to determine bacterial and fungal profile, their drug resistance patterns, and risk factors associated with blood stream infections.

Methods: A cross sectional study design was conducted from February 23 to June 23, 2020 at Ethiopian public health.

Antimicrobial Resistance Profiling and Molecular Epidemiological Analysis of Extended Spectrum β-Lactamases Produced by Extraintestinal Invasive Isolates From Ethiopia: The Presence of International High-Risk Clones ST131 and ST410 Revealed.

The treatment of invasive infections is a challenge because of the emergence and rapid spread of multidrug resistant strains. Particular problems are those strains that produce extended spectrum β-lactamases (ESBL's). Although the global characterization of these enzymes is advanced, knowledge of their molecular basis among clinical isolates in Ethiopia is extremely limited.

Corrigendum: Antimicrobial resistance surveillance in Ethiopia: Implementation experiences and lessons learned.

[This corrects the article DOI: 10.4102/ajlm.v7i2.

Extended-spectrum beta-lactamase production and multi-drug resistance among isolated in Addis Ababa, Ethiopia.

Background: The global emergence and spread of extended-spectrum beta-lactamases (ESBLs) producing have been threatening the ability to treat an infection. Hence, this study aimed to determine the prevalence of ESBL-producing and multi-drug resistance (MDR) (ESBLs-E) from different clinical specimens in Addis Ababa, Ethiopia.

Methods: A cross-sectional study was conducted from January 1 to May 30, 2017.

Antimicrobial resistance surveillance in Ethiopia: Implementation experiences and lessons learned.

Introduction: Antimicrobial resistance (AMR) poses a global threat. High levels of AMR to commonly used antibiotics have been reported in East Africa. A situation analysis of AMR in Ethiopia also indicated high resistance levels.