Uncovering the inhibitory potentials of leaf and its bioactive compounds against Plasmodium lactate dehydrogenase for malaria therapy.

Malaria control efforts have been hampered due to the emergence of resistant malaria parasite strains and the coinciding events of Covid-19. The quest for more effective and safe treatment alternatives is driving a slew of new studies that must be accelerated if malaria can be overcome. Due to its reported antimalarial activity, we studied the effects of extract and fractions of leaf on Plasmodium lactate dehydrogenase (pLDH) activity using an in vitro assay.

Essential oils from the leaves of six medicinal plants of Nigeria.

The chemistry of Cassia siamea L., C. occidentalis L.