Harnessing the Power of Zinc Oxide Nanoparticles for Accelerated Wound Healing and Antimicrobial Action.

Introduction: Zinc oxide nanoparticles (ZnONPs) have been the subject of substantial research by virtue of their utility across extensive downstream applications. Moreover, the ZnONPs are inexpensive, reliable, and easy to produce. Green synthesis employing biological systems, particularly plant extracts, has arisen as a subject of study in nanotechnology and is gaining importance due to its multiple applications in biology, chemistry, physics, and medicine.

The Impact of Bariatric Surgery on Weight Reduction and the Resolution of Comorbidities in Older Geriatric Populations of Saudi Arabia: A Retrospective Study.

Background Obesity is a significant health concern among older adults, leading to various comorbidities and reduced quality of life. Bariatric surgery (BS) has emerged as a potential intervention, but its efficacy in geriatric populations, particularly in Saudi Arabia, is not well-established. Aims This retrospective study aims to evaluate the impact of BS on weight reduction and comorbidity resolution in Saudi Arabian geriatric populations.

Critical Chest Wall Necrotizing Fasciitis Triggered by Herpes Zoster: A Case Report.

BACKGROUND Necrotizing fasciitis is an aggressive type of skin and soft tissue infection that results in necrosis of subcutaneous tissues, including muscle and fascia. Mixed bacteria, including gas-forming organisms, are usually identified. This report describes a 55-year-old male diabetic patient with herpes zoster involving the thoracic dermatomes complicated by skin infection, necrotizing fasciitis, chest wall abscess, and sepsis.

The Pathological Pattern of Breast Cancer in the Najran Region of Saudi Arabia: A Retrospective Study.

Background Breast cancer (BC) is the most widespread cancer on a global scale, and its prevalence is likewise significant in the Kingdom of Saudi Arabia. Nevertheless, the data accessible regarding the epidemiology and histopathological characteristics of BC in clinical practice is restricted and primarily confined to research endeavors. Aim This study aims to investigate the histopathological profile of women diagnosed with BC seeking treatment at King Khalid Hospital in the Najran region of the Kingdom of Saudi Arabia.

Green synthesis of zinc oxide nanoparticles from fruit peel extract: multifaceted potential in wound healing, antimicrobial, antioxidant, and anticancer applications.

This study focuses on the synthesis, characterization, and use of zinc oxide nanoparticles (ZnONPs) derived from fruit peel extract. ZnONPs are frequently synthesized utilizing a green technique that is both cost-effective and ecologically friendly. ZnONPs were characterized utilizing analytical techniques.

Antibacterial conductive self-healing hydrogel wound dressing with dual dynamic bonds promotes infected wound healing.

In clinical applications, there is a lack of wound dressings that combine efficient resistance to drug-resistant bacteria with good self-healing properties. In this study, a series of adhesive self-healing conductive antibacterial hydrogel dressings based on oxidized sodium alginate-grafted dopamine/carboxymethyl chitosan/Fe (OSD/CMC/Fe hydrogel)/polydopamine-encapsulated poly(thiophene-3-acetic acid) (OSD/CMC/Fe/PA hydrogel) were prepared for the repair of infected wound. The Schiff base and Fe coordination bonds of the hydrogel structure are dynamic bonds that can be repaired automatically after the hydrogel network is disrupted.

Assessment of the Desire and Readiness of Taif Residents for Heart Donation After Death.

Background/aim Heart transplantation is often the only preferable treatment for end-stage heart failure (HF); however, there are insufficient organ donors in Saudi Arabia. In this study, we aimed to understand the desire and readiness of Taif populations for heart donation after death. Methods We carried out a descriptive cross-sectional study among Taif residents in November 2022.

Prevalence of Fibromyalgia Syndrome in Taif City, Saudi Arabia.

Introduction Fibromyalgia syndrome (FMS) is a non-inflammatory, chronic disseminated musculoskeletal pain with unknown etiology. FMS patients suffer from generalized pain that markedly decreases their quality of life and productivity. Objective To investigate the prevalence of FMS and the correlation between people with positive screening criteria for FMS and their socio-demographic characteristics in Taif city.

IoT Framework for a Decision-Making System of Obesity and Overweight Extrapolation among Children, Youths, and Adults.

Approximately 30% of the global population is suffering from obesity and being overweight, which is approximately 2.1 billion people worldwide. The ratio is expected to surpass 40% by 2030 if the current balance continues to grow.

Physical Activity Monitoring and Classification Using Machine Learning Techniques.

Physical activity plays an important role in controlling obesity and maintaining healthy living. It becomes increasingly important during a pandemic due to restrictions on outdoor activities. Tracking physical activities using miniature wearable sensors and state-of-the-art machine learning techniques can encourage healthy living and control obesity.

Topical Application of Linn on Skin Wound Injury in Rats Accelerates the Wound Healing Process: Evidence from and Experimental Models.

Background: When the skin and tissues within the body are injured, the healing process begins. Medicinal herbs have been used to cure wounds since time immemorial. The antimicrobial and antioxidant activity possessed by may accelerate wound healing.

Machine Learning and Internet of Things Enabled Monitoring of Post-Surgery Patients: A Pilot Study.

Artificial Intelligence (AI) and Internet of Things (IoT) offer immense potential to transform conventional healthcare systems. The IoT and AI enabled smart systems can play a key role in driving the future of smart healthcare. Remote monitoring of critical and non-critical patients is one such field which can leverage the benefits of IoT and machine learning techniques.

Frequent clinical and radiological manifestations of the Novel SARS-CoV-2: A review article.

Coronavirus disease 2019 (COVID-19) is a highly infectious disease caused by the novel "severe acute respiratory syndrome coronavirus-2" (SARS-CoV-2) and is rapidly spreading worldwide. This review is designed to highlight the most common clinical features and computed tomography (CT) signs of patients with COVID-19 and to elaborate the most significant signs indicative of COVID-19 diagnosis. This review involved five original articles with both clinical and radiological features of COVID-19 published during Jan and Mar 2020.

Circulating long non-coding RNAs NKILA, NEAT1, MALAT1, and MIAT expression and their association in type 2 diabetes mellitus.

Background: Type 2 diabetes mellitus (T2DM) is a multifactorial disorder that leads to alterations in gene regulation. Long non-coding RNAs (lncRNAs) have become a major research topic as they are involved in metabolic disorders.

Methods: This study included a total of 400 study subjects; 200 were subjects with T2DM and 200 were healthy subjects.

The gap between ultrasonography and computed tomography in measuring the size of urinary calculi.

Objective: Due to a lack of studies regarding the need for computed tomography (CT) in measuring the size of each urinary calculus before surgery, this study was conducted to elucidate the difference between ultrasonography (US) and CT in measuring the size of urinary stones.

Methods: A retrospective review of 100 stones from 83 patients. Each urinary stone was measured using both US and CT; both measurements were then compared.

Awareness of Breast Cancer among Female Students and Faculty from Najran University, Najran, Saudi Arabia.

Background: Breast cancer (BC) is the leading malignancy among women in Najran, Saudi Arabia. However, not much is known about the public's awareness of BC. This study explored the general knowledge, early warning signs, risk factors and sources of information about BC.

Prevalence of Keratoconus in a Refractive Surgery Population.

Objective: This study examined the prevalence of keratoconus among patients who were interested in undergoing refractive surgery. Corneal tomography measurements were used to help detect keratoconus.

Methods: Adult subjects who presented to the private hospital Cataract and Refractive Surgery Unit (Abha, Saudi Arabia) for refractive surgery evaluation were considered for inclusion in this cross-sectional, retrospective study.

5-year follow-up of combined non-topography guided photorefractive keratectomy and corneal collagen cross linking for keratoconus.

Aim: To evaluate the visual outcomes of simultaneous non-topography guided photorefractive keratectomy (PRK) and corneal collagen cross-linking (CXL) in eyes with keratoconus 5y after the procedure.

Methods: Prospective, interventional, non-randomized, and non-controlled case series design was used. Sixty eyes of 30 patients (16 males and 14 females; age: 21-41y) with mild, non-progressive (stages 1-2) keratoconus were enrolled.

Long-term use of 0.003% tacrolimus suspension for treatment of vernal keratoconjunctivitis.

Purpose: To evaluate the safety and efficacy of 0.003% tacrolimus suspension for the treatment of refractory vernal keratoconjunctivitis (VKC).

Materials And Methods: This prospective study included 40 eyes of 20 patients with severe VKC.

Tacrolimus Ointment for Treatment of Vernal Keratoconjunctivitis.

Purpose: To evaluate the safety and efficacy of tacrolimus 0.1% ointment for the treatment of refractory vernal keratoconjunctivitis (VKC).

Materials And Methods: This prospective, nonrandomized case series enrolled 20 patients (40 eyes) with severe VKC, who were treated with tacrolimus 0.

Long-term follow-up of tacrolimus ointment for treatment of atopic keratoconjunctivitis.

Purpose: To evaluate the long-term clinical outcomes of 0.1% tacrolimus dermatologic ointment (Protopic) in cases of refractory atopic keratoconjunctivitis (AKC).

Design: Prospective, nonrandomized, noncontrolled case series.

Visual outcome of pars plana vitrectomy for retained lens fragments after phacoemulsification.

Purpose: To evaluate the visual outcome of patients who underwent pars plana vitrectomy (PPV) for posteriorly dislocated lens fragments after phacoemulsification.

Methods: A retrospective chart review was conducted of all patients who had PPV for posteriorly dislocated lens fragments after phacoemulsification between January 2000 and September 2004 in the Vitreoretinal Service at King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia. Demographics, preexisting eye diseases, details of the previous cataract surgery, findings at presentation, details of the vitreoretinal procedures, final visual acuity, and complications observed during the follow-up were evaluated.

Corneal perforation associated with topically applied gatifloxacin.

Purpose: To document the development of corneal perforation after using gatifloxacin to treat inflamed pterygium.

Methods: A 30-year-old man developed corneal perforation after using gatifloxacin to treat inflamed pterygium.

Results: After treatment with gatifloxacin was stopped, the perforation was managed by applying cyanoacrylate glue, followed by pterygium excision.