Antioxidant activities for superoxide dismutase in patients with Crohn's disease.

Background: In this study, we aimed to determine the levels of antioxidant activity for superoxide dismutase (SOD) enzymes in patients with Crohn's disease (CD) to investigate their contribution to tissue injury in CD.

Methods: Forty-two patients with CD and 38 matched healthy subjects (control group) were recruited. SOD enzymatic activity was measured by purely chemical system based on NAD(P)H oxidation.

Presenting features of childhood-onset inflammatory bowel disease in the central region of Saudi Arabia.

Objective: To investigate the presenting features of childhood-onset inflammatory bowel disease (IBD) in the central region of Riyadh, Saudi Arabia and to compare with those reported in the literature.

Methods: This is a retrospective review of medical records of children below 18 years of age at onset of symptoms with confirmed diagnosis of IBD for age, gender, family history, presenting clinical and laboratory findings in the Divisions of Pediatric and Adult Gastroenterology, King Khalid University Hospital (which provides free health care) and the Department of Gastroenterology Al Mofarreh Poly Clinic, Riyadh, Saudi Arabia, between January 1993 and December 2010.

Results: Two hundred and eighteen children diagnosed with IBD with predominance of males in Crohn's disease (CD) (56%) and females in ulcerative colitis (UC) (59%).

Crohn's disease in a Saudi outpatient population: is it still rare?

Background/aim: To determine the epidemiology of Crohn's disease (CD) in an outpatient clinic and compare it with data previously reported from different centers in the Kingdom of Saudi Arabia and outside.

Materials And Methods: The medical records of all patients with CD seen in the clinic in the period from January 1993 through December 2007 were reviewed. The demographic, clinical data and methods of diagnosis were retrieved.

Lipid peroxides in patients with inflammatory bowel disease.

Background/aims: In this study, we aimed to determine the levels of malondialdehyde (MDA) in patients with inflammatory bowel disease (IBD) to investigate its contribution to tissue injury in IBD.

Materials And Methods: Forty-two patients with IBD (24 cases of Crohn's disease and 18 cases of ulcerative colitis) and 38 matched healthy subjects (control group) were considered for study. MDA levels were quantified by the measurement of thiobarbituric acid reactive substances.

Histological and laboratory features of patients undergoing liver biopsy at a university hospital in Central Saudi Arabia.

Objective: To identify the most common liver pathologies seen in our center, to find the prevalence of advanced fibrosis and cirrhosis in patients with chronic hepatitis B and C, and to correlate the histological and laboratory features of the most common diseases and compare between them.

Methods: Liver biopsy procedures performed in our Gastroenterology Unit at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia were traced from records between the years 1997-2003. Clinical, histopathological, and laboratory features were recorded.