Publications by authors named "Abdulrahman Almalki"

Aim: The purpose of this study is to investigate the interchangeability of newly acquired, short-term used, and long-term used semi-adjustable articulators.

Materials And Methods: Metal analogs of partially dentate maxillary and mandibular arches were mounted on twelve semi-adjustable Stratos 300 articulators, divided into three groups based on usage over time: New, short-term used (<2 years), long-term used (>2 years) articulators. Each articulator was calibrated according to manufacturer guidelines, ensuring consistency.

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Background: The World Health Organization (WHO) has identified carbapenem-resistant Pseudomonas aeruginosa (CRPA) as one of the three critical priority pathogens. There is scarce literature evaluating the treatment outcomes in patients with CRPA infections treated with traditional non-carbapenem β-lactam (NCBL) agents. Thus, this study aims to assess the effectiveness of traditional NCBL compared to novel β-lactam agents (NVL) for treating non-carbapenem β-lactam -susceptible CRPA.

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Background Diabetes mellitus is one of the causes to use complementary and alternative medicine (CAM), which can be classified into nutritional, psychological and physical. The study's objective was to estimate the prevalence and pattern of using CAM among patients with diabetes mellitus who followed the endocrine and diabetes center in Taif. Materials and methods A cross-sectional study was carried out in Taif city from 1 June to 31 July 2023 among diabetic patients aged 14 years and above who followed the endocrine and diabetes center.

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Background The COVID-19 pandemic has significantly influenced public perceptions and behaviors related to vaccination. Understanding parental attitudes, knowledge gaps, and vaccination practices post-pandemic is crucial for informing effective public health strategies. This study aimed to investigate parental attitudes, knowledge, and practices toward routine childhood vaccination in the post-COVID-19 era, emphasizing shifts in perspectives and implications for vaccination strategies.

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Article Synopsis
  • Brucellosis is a widespread zoonotic disease that predominantly affects spinal health, yet there's limited information on the best antibiotic treatments for spinal brucellosis.
  • A retrospective study conducted over 11 years in Makkah, Saudi Arabia, analyzed the treatment outcomes of 35 spinal brucellosis patients, focusing on their age, symptoms, and antibiotic regimens used.
  • The most common treatment regimen was a combination of streptomycin, doxycycline, and rifampicin, with a low failure rate; however, some patients required surgical intervention, indicating the seriousness of the condition.
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The search for antiviral medications is greatly influenced by the hunt for potent inhibitors of viral proteins. To find possible inhibitors of the RNA binding activity of the Marburg virus VP35 protein, we used a thorough in silico drug discovery approach in this investigation. A comprehensive virtual screening process, followed by a detailed MMGBSA analysis, led to the discovery of four potential inhibitory compounds viz.

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Unsplinted attachment systems for implant overdentures offer various benefits for edentulous patients, including cost-effectiveness, enhanced cleansability, and less need for manual dexterity. This article describes a facially driven digital workflow for fabricating a maxillary implant overdenture retained by conometric-style attachments (Atlantis® Conus) with a palateless design opposing an implant overdenture retained by standard attachments (LOCATOR®). This procedure provides a predictable and accurate technique to digitally scan the master casts with wax rims for articulation and to guide the digital teeth design set-up for a predictable esthetic outcome.

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Introduction: Schistosomiasis is a parasitic infection caused by schistosome invasion of blood circulation. Neuroschistosomiasis is a severe cerebral complication that accounts for less than 2.3% of reported cases.

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Background Low back pain (LBP) is common and considerably impacts daily lives across all age groups. MRI is not frequently used as a first-line investigation for patients presenting with LBP, except in the presence of red-flag symptoms. This study aimed to use pain severity and its impact as a predictor for MRI findings to help physicians decide whether a patient needs an MRI.

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Background: Patient satisfaction is crucial for assessing healthcare quality and identifying strengths and weaknesses in healthcare organizations. In Saudi Arabia, the Ministry of Health (MOH) implemented the Patient Experience Measurement Program to enhance patient experience and healthcare quality. This study aimed to identify specific aspects of patient satisfaction with dental visits in Saudi Arabia to improve dental care quality and inform dental services development.

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Introduction Carpal tunnel syndrome (CTS) is a peripheral neuropathy that happens when the median nerve is compressed by the transverse carpal ligament within the carpal tunnel. Public awareness is crucial for early detection and intervention; therefore, this study aims to assess the awareness of CTS among the adult population in the western region of Saudi Arabia. Methods The study design was a cross-sectional study where 1400 participants (although 1199 answers were included) from the western region were randomly asked to fill in an online questionnaire that was delivered to them via social media applications.

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Article Synopsis
  • Chemotherapy resistance, particularly to etoposide, significantly contributes to treatment failure in acute myeloid leukemia (AML).
  • This study focused on understanding etoposide resistance in AML using HL60 cell lines, identifying three resistant clones (HL60-EtopR H1A, H1B, H1C) with notably higher resistance levels.
  • Gene expression profiling revealed the upregulation of src tyrosine kinase family genes in resistant cells, indicating a potential target for further research to overcome resistance using Src inhibitors.
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Background and objective Aesthetic procedures are one of the most commonly performed medical procedures. Surgical and non-surgical cosmetic treatments that are routinely performed include breast augmentations, rhinoplasty, botulinum toxin, and fillers. Several factors contribute to the increase in the popularity of these procedures, including body image dissatisfaction, the opinion of peers, and surgeon-related factors such as the surgeon's reputation, board certification, or years of experience.

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  • Primary systemic vasculitis can show a variety of symptoms, including general issues like fever and body aches, as well as specific organ damage.
  • The text describes two cases that mimic primary systemic vasculitis: cholesterol embolisation syndrome and Kaposi sarcoma, both displaying symptoms like blue toe syndrome and skin rashes.
  • The report emphasizes the difficulty of diagnosing these conditions accurately and aims to provide guidance on how to differentiate them from primary systemic vasculitis.
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Background: This study aimed to ascertain the prevalence of dental anomalies and their ability to estimate sex status.

Material And Methods: This cross-sectional radiographic study was based on the evaluation of dental anomalies of Saudi children aged between 5 and 17 years. A total of 1940 orthopantomograms (OPG) were screened, of which 1442 were included.

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Background: Idiopathic spinal epidural arachnoid cysts (SEACs) are rare and may cause myelopathy and cord compression. They typically arise from a congenital defect in the dura that communicates with the intrathecal subarachnoid space. Although the ideal treatment of SEACs is direct dural repair and cyst excision, there is as yet no clear standard of care for the management of these lesions.

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Analog design protocols through the use of wax-ups are highly variable, technique sensitive, and operator dependent. Current digital smile design and treatment planning tools facilitate simplified processes based on the patient's face as well as specific esthetic and functional needs of the individual patient. The initial smile design achieved with an advanced and novel smile design software enables a straightforward treatment plan and execution, even in complex esthetic situations where various restorations are needed.

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Introduction: Fungal infection of the central nervous system has become more common over the past two decades. It is frequently diagnosed in patients with underlying pathological conditions. We herein report a case of rhino-orbital-cerebral mucormycosis by outlining the clinical presentation, radiological images, histopathological findings, management plan, and its clinical outcome.

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Diabetes affects the developing enamel by altering the mineralization process, which can have a detrimental effect on oral health. The objectives of this study were to examine the ultrastructure and composition of surface enamel in primary teeth of diabetic children and its clinical implications. Hundred extracted primary teeth from diabetic children (Test group: n = 50) and healthy children (Control group: n = 50), between 6 and 12 years of age, were subjected to scanning electron microscopy to qualitatively examine the enamel surface.

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Background: The metabolic pathways can be affected by dysregulation in thyroid hormone levels which in turn can arise from environmental chemical exposure. This study investigated the association of selected trace elements with thyroid disorders in a Saudi population.

Methods: Urine samples collected from 100 participants (50 thyroid disorder patients and 50 controls) were analyzed to determine trace elements using inductively coupled plasma-mass spectrometer.

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Background: Obesity among children became of high concern. Obesity can affect many health aspects including muscular strength. Downhill walking is a useful intervention to enhance muscular strength, especially in older adults.

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Nowadays, phthalates widely employed in many products are distributed around us which contributed to the development of many chronic diseases. We investigated the incidence of type 2 diabetes mellitus (T2DM) in Saudi subjects and correlated it with urinary phthalate metabolites' screening study.We selected a total of 100 cases early diagnosed as type 2 diabetes mellitus (FBS ≥ 126 mg/dl, PP 2 h, ≥ 140 mg/dl) and 50 normal subjects (FBS ≤ 90 mg/dl) as control.

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Objective: The objective of the study is to determine the role of Lateral Pterygoid Muscle LPM in the articular disc displacement ADD, which is considered controversial due to the variations in the pattern of insertion of the Superior Lateral Pterygoid Muscle SPLM.

Background: It is well understood that the superior head of the lateral pterygoid muscle has only a single insertion pattern among individuals, in which the muscle is attached to the articular disc and capsule. However, recent findings in many studies have shown a noticeable variation in the insertion pattern of the upper LPM.

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