Patients with diabetes polyneuropathy are at a heightened risk for developing foot ulcers, often due to dynamic plantar foot pressure patterns that lead to increased pressure and shear forces in specific foot areas. This study aimed to evaluate the effects of foot insoles on peak pressure and the pressure-time integral in patients with polyneuropathy diabetic foot ulcers over a twelve-week period followed by an eight-week follow up. : This was a prospective, randomized, double-blinded, controlled clinical trial involving 60 patients aged between 50 and 65 years of both genders.
View Article and Find Full Text PDFBerberine (BER) and Cyperus rotundus rhizomes extract (CRE) are phytochemicals characterized by broad-spectrum pharmacological activity that could tackle the side effects of conventional mastitis therapies, however, they undergo a modest bioavailability. In the current study, nanoformulations of BER and CRE chitosan hydrogel (BER/CH-NPs, CRE/CH-NPs) were investigated for their antibacterial, antioxidant, anti-inflammatory and anti-apoptotic effects against S. aureus-induced mastitis in a rat model.
View Article and Find Full Text PDFThis work focused on the transformation behavior of the emerging beaytlmethodeyammonium chbride (BAC-12) disinfectant existed in the treatment of medical sewage during its disinfection treatment. The degradation ability of ozone (O) to BAC-12 was the best, followed by UV/NaOCl, UV, and NaOCl. The enhancement of BAC-12 in UV/NaOCl system is caused by the combined effect of UV photolysis, reactive chlorine species (RCS), and •OH.
View Article and Find Full Text PDFBackground: Obsessive-compulsive disorder (OCD) is a psychiatric condition characterized by recurrent, unwanted thoughts (obsessions) and repetitive behaviors (compulsions) performed to relieve distress related to the obsessions. For patients with severe illness refractory to first-line pharmacotherapy and psychotherapy, neurosurgical treatments such as deep brain stimulation (DBS) and stereotactic lesioning are an option. The choice between DBS and lesioning is often driven by patient preference, but these options are not mutually exclusive.
View Article and Find Full Text PDFThe study investigated the impact of utilizing leaf powder (RNL) as a phytogenic feed additive on performance, blood markers, intestinal microbiology and histomorphology in broiler chicken. One hundred eighty day-old Cobb broiler chicks were randomly divided into four treatment groups having three replicates with fifteen birds each. Four iso-caloric and iso-nitrogenous diets primarily based on maize-soybean were formulated, viz.
View Article and Find Full Text PDF2-(2H-benzotriazol-2-yl)-4,6-di-tert-pentylphenol (UV328) is a commonly used benzotriazole ultraviolet stabilizers (BUVs) with bioaccumulative properties. Since it's stubbornly degraded in the environment, it poses significant environmental risks in soil. However, the removal of UV328 from soil is challenging, and existing treatment methods have low efficiency.
View Article and Find Full Text PDFThis study investigated the effect of supplementation of leaf powder (MSLP) on the production performance of broiler chicken. Ven Cobb broiler chicks (240 day-old male chicks) were distributed randomly into four treatments, each replicated four times, with 15 birds per replicate. The diets formulated were T1 (control) given basal diet only, T2 (basal diet +1.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
October 2024
The well-known antibiotic gentamicin (GEN) works well against a variety of pathogenic bacteria, nevertheless its therapeutic use might be limited by the possibility of nephrotoxicity. The naturally occurring flavonoid galangin (GAL) has several interesting anti-inflammatory and antioxidant properties. The present study evaluated the nephroprotective effect of GAL on GEN-induced renal injury.
View Article and Find Full Text PDFSalinity negatively impacts crop production by affecting physiological and biochemical processes in plants. This study investigates the effectiveness of Nano-ZnO (NZn), proline (PA), Nano-TiO (NTi), Nano-SiO (NSi)), and biochar inoculated with (OSBS) in enhancing wheat tolerance to salinity stress. Pot experiments were conducted under saline conditions with varying rates of biochar and foliar applications.
View Article and Find Full Text PDFTwo forms of morphologically transformed glauconite (GL) involved exfoliated nanosheets (EXG) and nanorods (GRs), which were synthesized by facile exfoliating and scrolling modification under sonication. The two advanced forms (EXG and GRs) were applied as enhanced adsorbents for U(vi) ions and compared with using raw glauconite. The developed GRs structure displays higher saturation retention properties (319.
View Article and Find Full Text PDFThe uncontrolled administration of the cisplatin drug (CPTN) resulted in numerous drawbacks. Therefore, effective, affordable, and biocompatible delivery systems were suggested to regulate the loading, release, and therapeutic effect of CPTN. Zinc phosphate/hydroxyapatite hybrid form (ZP/HP) and core-shell nano-rod morphology, as well as its functionalized derivative with cellulose (CF@ZP/HP), were synthesized by the facile dissolution precipitation method followed by mixing with cellulose fibers, respectively.
View Article and Find Full Text PDFAn important concern is the availability of clean drinking water, which is an essential need for human survival. This issue arises due to the existence of hazardous micropollutants originating from various emission sources. Nanotechnology aids in the mitigation of micropollutants by assimilating and counteracting their effects, hence diminishing their influence on water and other ecosystems.
View Article and Find Full Text PDFThis work was designed to assess the impact of varying zeolite concentrations in diet and litter to enhance broiler's growth performance, immunity, and litter quality. A complete random arrangement was used for distributing 525 unsexed "Cobb 500" broiler chicks into seven treatments (75 chick / treatment), each treatment divided into 3 replicates (25 chicks / replicate). The 1st group (control one) received the recommended basal diet.
View Article and Find Full Text PDFThis investigation aimed to evaluate the impact of immersion (IM) riboflavin treatment on the hatchability, production efficiency, and carcass characteristics of Japanese quail eggs. A total of 260 eggs of Japanese quail birds were used for hatching and were randomly divided into 4 treatments with 5 replicates (13 eggs/replicate) in a fully randomized design. Hatching eggs were immersed in riboflavin for 2 min before incubation.
View Article and Find Full Text PDFAn advanced form of magnesium-rich hydroxyapatite (Mg·HAP) was modified with two types of biopolymers, namely chitosan (CH/Mg·HAP) and β-cyclodextrin (CD/Mg·HAP), producing two types of bio-composites. The synthesized materials were developed as enhanced carriers for levofloxacin to control its loading, release, and anti-inflammatory properties. The polymeric modification significantly improved the loading efficiency to 281.
View Article and Find Full Text PDFThe hazard of diseases created by S. Enteritidis and S. Typhimurium is relatively high in turkey meat products.
View Article and Find Full Text PDFThis study investigated the effect of different levels of zeolite in laying hen (Silver Montazah) diet and litter on productive performance, egg quality criteria, and economics during the second stage of production (40-56 wk of age). An experiment with a 3 × 4 factorial design was performed to study the effects of four levels of zeolite (0, 10, 15, and 20 g/kg feed) in the diet and three levels of zeolite (0, 1.5, and 2 kg/m) in the litter.
View Article and Find Full Text PDFThe increase in antibiotic residues poses a serious threat to ecological and aquatic environments, necessitating the development of cost-effective, convenient, and recyclable adsorbents. In our study, we used cellulose-based layered double hydroxide (LDH) as an efficient adsorbent and nanocarrier for both sulfamethoxazole (SMX) and cefixime (CFX) residues due to their biodegradability and biocompatibility. Chemical processes are measured according to green chemistry metrics to identify which features adhere to the principles.
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