Publications by authors named "Abdulrahman Alkhalifa"

Background: The menopausal transition significantly affects cardiometabolic health, primarily due to changes in reproductive hormones, particularly decreased estrogen levels and relative androgen excess. Adult Muslim women, both pre-and post-menopausal, are mandated to observe Ramadan intermittent fasting (RIF) every year. Therefore, the current study was designed to investigate RIF's effects on pre-menopausal (PRE-M) and post-menopausal (POST-M) healthy women's cardiometabolic health markers.

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  • - Polycystic ovary syndrome (PCOS) impacts women's reproductive, metabolic, and mental health, and this study compared nutritional intake and body fat distribution between 42 PCOS patients and 63 control women aged 20-45 years.
  • - Significant differences were found in dietary intake, with the PCOS group consuming more total calories, carbohydrates, and certain vitamins, while the control group had higher levels of dietary fiber and healthy fats.
  • - Biochemical analyses revealed that PCOS patients had higher testosterone and lower vitamin D levels compared to controls, indicating distinct health implications for women with PCOS despite both groups being predominantly overweight or obese.
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Background And Objectives: Hereditary spastic paraplegias (HSPs) are heterogenous genetic disorders characterized by progressive pyramidal tract involvement. SPG76 is a recently identified form of HSP, caused by biallelic calpain-1 (CAPN1) variants. The most frequently described MRI abnormality in SPG76 is mild cerebellar atrophy and non-specific white matter abnormalities were reported in only one case.

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Ramadan intermittent fasting (RIF) is a monthlong practice in which Muslims fast during the whole day from sunrise to sunset. During this month, fasting people change their dietary behavior and alter their eating hours from day to night. The objective of the current study was to examine the effect of RIF on dietary consumption, anthropometric indices, and metabolic markers in healthy premenopausal (PRE-M) and postmenopausal (POST-M) Saudi women.

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  • Tendons play a role in various conditions, from birth defects to injuries, and understanding their development is crucial for advances in tissue engineering and regenerative medicine.
  • The research focuses on the chick embryo as a model to study Achilles tendon development, overcoming challenges in accurately isolating and testing these small and delicate structures.
  • A new "marking protocol" was created to enhance tendon isolation, revealing significant differences in mechanical properties compared to traditional methods, and aligning with previous findings on cell-level mechanics.
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Nutritional risk in children is associated with food safety. This is the first study to identify the food type consumed by 6-17-year-old school-going children in Saudi Arabia. Eight permitted artificial food color additives, including Tartrazine (E102), Sunset Yellow (E110), Carmoisine (E122), Allura Red (E129), Indigo Carmine (E132), Brilliant Blue (E133), Fast Green (E143), and Black PN (E151), and two non-permitted ones, Erythrosine (E127) and Red 2G (E128), were determined using 24-h dietary recall questionnaires.

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The second most biggest cancer worldwide is breast cancer. There is an increasing need for safer, effective, and affordable drug candidates from natural sources to treat breast cancer. In the present investigation, the anticancer effect of Bouché (.

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This study investigated the chemical composition, in vivo antioxidant, and antihyperlipidemic potential of Ajwa date polyphenol extract (DPE). Chemical analysis revealed that the Ajwa dates contain substantial amounts of carbohydrates, energy, potassium, iron, polyphenols, and flavonoids. In vivo studies showed that feeding rats with cholesterol-rich diets significantly (p ≤ 0.

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Background: By 2022, it is estimated that the rate of female obesity (78%) in Saudi Arabia will almost double that of males (41%). Despite being mainly attributed to poor diet, sedentary lifestyle, and a lack of health awareness, behavioral modification interventions are relatively new to the population; bariatric surgery continues to be the treatment of choice for comorbidities. However, neither pre nor postoperative diet and exercise are promoted.

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Mobile technology has been used successfully for promoting health and weight loss and for treating obesity. There is a high prevalence of smartphone and tablet users among the Saudi population. This study aimed to identify whether current Arabic weight-loss apps had features that adhered to evidence-informed practices.

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Background: Weight gain and its related illnesses have become a major public health issue across the world, with Saudi Arabia and other Gulf countries seeing dramatic increases in obesity and overweight, and yet there is very little information on how to intervene with this demographic due to cultural and linguistic barriers. As the use of smartphones and apps has also increased in the region, information communication technologies could be a cost-effective means of facilitating the delivery of behavior-modification interventions directly to the target population. Although there are existing apps that offer lifestyle-modification tools, they do not give consideration to the evidence-based practices for weight management.

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Background: Overweight and obesity are international public health issues. With mobile and app use growing globally, the development of weight loss apps are increasing along with evidence that interventions using technology have been effective in the treatment of obesity. Although studies have been conducted regarding what content health professionals would recommend within weight loss apps, there are limited studies that explore users' viewpoints.

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Juices of edible fruits from Opuntia ficus-indica (L.) Miller, commonly named prickly pears or Indian figs, were analysed for amino acids using an automated amino acid analyser run in the high-resolution physiological mode. Emphasis was put on the detection of free taurine (Tau), but Tau could be detected neither in different cultivars of prickly pears from Italy, South Africa and the Near East nor in commercially available prickly pear juices from the market.

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  • The study explores the presence of non-proteinogenic amino acids (AAs) in the edible fruits of the date palm (Phoenix dactylifera L.), highlighting the lack of prior research in this area compared to common proteinogenic AAs.
  • Twelve cultivars of date fruits were analyzed using advanced techniques like automated ion-exchange chromatography and GC-MS, revealing the presence of several non-proteinogenic AAs in varying amounts, such as 5-hydroxypipecolic acid and 1-aminocyclopropane-1-carboxylic acid.
  • The research also includes enantiomeric analysis, finding very low levels of D-amino acids relative to their L-counterparts, and discusses the
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