Publications by authors named "Abdulmonim A Alqasim"
Objectives: Diabetes mellitus is associated with oxidative stress that leads to inflammation and diabetic nephropathy. This study aimed to determine the possible renoprotective effects of the antioxidants melatonin, vitamin D and vitamin E in diabetic rats.
Methods: We divided 108 albino rats into 12 groups.
Background: Diabetes mellitus (DM) is a serious chronic disease, with multiple complications including hepatopathy associated with imbalance of the oxidative status. The purpose of this study is to observe possible protective effects of vitamin-D and melatonin on glucose profile, antioxidant-oxidant status, lipid peroxidation, and histopathological protection of the liver in streptozotocin-induced diabetic rats.
Methods: Eighty three male albino rats were divided into nine groups as follows: ( = 10) Normal control rats; ( = 8) were normal rats treated with melatonin only; ( = 10) were normal rats treated with vitamin D only; ( = 9) were diabetic rats, which received no medications; ( = 8) were diabetic rat treated with insulin only; ( = 10) were diabetic rats treated with melatonin only; ( = 9) were diabetic rats treated with melatonin and insulin; ( = 9) were diabetic rats treated with vitamin D only; ( = 10) were diabetic rats treated with vitamin D and insulin.