Unraveling the role of salt-sensitivity genes in obesity with integrated network biology and co-expression analysis.

Obesity is a multifactorial disease caused by complex interactions between genes and dietary factors. Salt-rich diet is related to the development and progression of several chronic diseases including obesity. However, the molecular basis of how salt sensitivity genes (SSG) contribute to adiposity in obesity patients remains unexplored.

General and Postbariatric Nutritional Knowledge among Patients Undergoing Bariatric Surgery.

Purpose: The prevalence of obesity and the number of bariatric surgeries are increasing in Saudi Arabia. Studies evaluating nutritional knowledge, especially in Middle Eastern countries, are limited. Therefore, this study was conducted to examine the general and postbariatric nutritional knowledge related to dietary recommendations among patients undergoing bariatric surgery.

Public perception of bariatric surgery.

To investigate the public perception of morbid obesity and bariatric surgery in Saudi Arabia. Methods: A cross-sectional study was conducted between November 2016 and November 2017 in Jeddah, Saudi Arabia, including Saudis aged ≥18 years. Medical students, physicians, and individuals who underwent bariatric surgery were excluded.

Surgical site infection following abdominal surgery: a prospective cohort study.

Background: Surgical site infection (SSI) is one of the most common complications of abdominal surgery and is associated with substantial discomfort, morbidity and cost. The goal of this study was to describe the incidence, bacteriology and risk factors associated with SSI in patients undergoing abdominal surgery.

Methods: In this prospective cohort study, all patients aged 14 years or more undergoing abdominal surgery between Feb.

Transfusion Practices Among General Surgeons at a Tertiary Care Center: a Survey Based Study.

Introduction: Blood transfusion practices affect both patient's outcomes and utilization of institutional resources. Evidence shows that liberal blood transfusion has a detrimental effect on patient's outcome. A restrictive approach of blood transfusion is recommended by current clinical guidelines.

Bariatric surgery improves knee function and not knee pain in the early postoperative period.

Background: Obesity remains the strongest predictor of knee osteoarthritis (OA). Studies have reported improvement in knee pain and function post-bariatric surgery secondary to weight loss and reduced mechanical loading, yet others found increased rates of total knee arthroplasty (TKA) in that patient population. To address this controversy, our study aimed to further assess the effect of surgically induced, "rapid" weight loss on knee pain and function.

Level of evidence of abdominal surgery clinical research in Saudi Arabia.

To quantify and evaluate the level of evidence (LOE) of Saudi publications in abdominal surgery and correlate the obtained results with that of other similar national and international studies. Methods: Study design was a systemic review. Literature search strategy was developed to retrieve available articles between January 2000 and  December 2016 that are related to abdominal surgery utilizing PubMed and Google Scholar.

Transient small bowel intussusception in an adult: case report with intraoperative video and literature review.

Background: The term intussusception refers to invagination of a segment of the gastrointestinal tract into the lumen of an adjacent segment. This is a rare entity and it is more prevalent in children and less common in adults. The diagnosis of intussusception in adults is difficult as a result of the nonspecific signs and symptoms.

A case report: Cecal volvulus caused by Meckel's diverticulum.

Introduction: Meckel's diverticulum is the most common congenital anomaly of the small intestine. Common complications related to Meckel's diverticulum include hemorrhage, intestinal obstruction and inflammation. Acute large bowel obstruction is a rare complication of Meckel's diverticulum and in the presented case it is caused by volvulus.

Preparation of soluble stable C₆₀/human serum albumin nanoparticles via cyclodextrin complexation and their reactive oxygen production characteristics.

Aims: The stability of solutions of fullerene C₆₀ with human serum albumin (C₆₀/HSA) has not been studied in detail. In this study, we report on the preparation of stable C₆₀/HSA solutions that are formed via the formation of C₆₀/HP-β-CyD nanoparticles, i.e.

Crystallization of a new polymorph of acetohexamide from 2-hydroxybutyl-β-cyclodextrin solution: form VI with a high aqueous solubility.

A new polymorph of acetohexamide (Form VI) was prepared via the formation of a complex with 2-hydoxybutyl-β-cyclodextrin (HB-β-CD) in aqueous solution. An alkaline solution of acetohexamide and HB-β-CD was adjusted to pH 4.0 by titration with hydrochloric acid.

Morbidity of hand-assisted laparoscopic splenectomy compared to conventional laparoscopic splenectomy: a 6-year review.

Background: Laparoscopic splenectomy (LS) has several advantages over the open procedure but can be technically demanding when performed in patients with massive splenomegaly. We hypothesized that patients who undergo hand-assisted LS (HALS) may experience the benefits of LS while having their enlarged spleens removed safely.

Methods: We reviewed the charts of patients who underwent HALS or LS between January 2003 and June 2008.

Laparoscopic accessory splenectomy: the value of perioperative localization studies.

Background: Laparoscopic splenectomy is an effective treatment for many patients with immune thrombocytopenic purpura (ITP) who fail or relapse after treatment with steroids. Patients with an incomplete response to splenectomy and those who experience recurrence of symptoms should be evaluated for the presence of an accessory spleen. The clinical effectiveness of laparoscopic excision of an accessory spleen after a previous splenectomy for ITP has varied in different studies.

Is right laparoscopic donor nephrectomy right?

Introduction: Laparoscopic donor nephrectomy has become the standard of care in many renal transplant centers. Many centers are reluctant to perform right laparoscopic donor nephrectomies, primarily due to concerns about transplanting a kidney with a short renal vein.

Methods: A retrospective review of 26 right and 24 left consecutive donor nephrectomies and their recipients was performed.