Urinary RBP as an Independent Predictor of Renal Outcome in Diabetic Nephropathy.

Background: Renal tubular impairment is prevalent in diabetic nephropathy (DN) and the histological severity predicted renal outcome. Biomarkers of tubular injury also increased in the urine of DN patients. The retrospective study aimed to assess the prognostic value of clinically widely applied urinary tubular injury markers, retinol-binding protein (RBP), 2-microglobulin (2-MG) and N-acetyl--D-glucosaminidase (NAG) in DN.