Antiplasmodial Activity of Probiotic YZ01 in ANKA Infected BALB/c Mice.

Malaria remains a significant global health challenge, with the deadliest infections caused by . In light of the escalating drug resistance and the limited effectiveness of available vaccines, innovative treatment approaches are urgently needed. This study explores the potential of the probiotic YZ01, isolated from traditionally fermented kindirmo milk, to modify host responses to ANKA infection.

Evaluating hepatitis B screening, prevalence, vaccination coverage, and linkage to care in Abuja, Nigeria: insights from a cross-sectional study.

Background: Hepatitis B virus (HBV) is a major global health threat, especially in Sub-Saharan Africa, where Nigeria has a prevalence exceeding 8%. Despite the availability of effective vaccines, inadequate coverage and lack of awareness have resulted in high rates of chronic infections and HBV-attributable liver disease. The study aimed to raise awareness of HBV, enroll participants for HBV screening, determine HBV prevalence across various communities, vaccinate negative cases and link positive cases to care.

Evaluation of the double-zone hemolysis (DZH) test for the detection of livestock-associated methicillin-resistant .

Unlabelled: Livestock-associated methicillin-resistant (LA-MRSA), such as clonal-complex (CC)398, are of clinical relevance due to their multi-drug resistance profiles, adding to the overall burden of MRSA in humans. The objective was to evaluate the double-zone hemolysis (DZH) test as a simple and reliable method for detecting LA-MRSA in the clinical microbiology laboratory. isolates assigned to CC398 ( = 183; 152 MRSA/31 methicillin-susceptible [MSSA]), CC1 ( = 44; MRSA), and other CCs ( = 144; 94 MRSA/50 MSSA) were investigated.

Developmental and Functional Outcomes Amongst Culturally and Linguistically Diverse Autistic Children.

Children typically learn by attending to other people. Autism traits may impact access to social stimuli fundamental to early learning, increasing children's likelihood of a learning disability. Recent reports have highlighted that Autistic children from minority backgrounds have a higher likelihood of co-occurring intellectual disability.

Road injuries, labor productivity, and economic growth in Africa: A panel study.

Background And Aims: Globally, millions of people suffer from road injuries, with Africa having the highest burden of road injury deaths. This public health problem has the potential to reduce labor productivity and hence hamper economic growth, especially on the African continent. This study, to the best of the authors' knowledge, therefore seeks to provide the first empirical evidence of the interaction or combined effect of road injuries and labor productivity on economic growth in African countries.

Deep learning ResNet34 model-assisted diagnosis of sickle cell disease microcolumn isoelectric focusing.

Traditional methods for sickle cell disease (SCD) screening can be inaccurate and misleading, and the early and accurate diagnosis of SCD is crucial for effective management and treatment. Although microcolumn isoelectric focusing (mIEF) is effective, the hemoglobinopathies must be accurately identified, wherein skilled personnel are required to analyse the bands in mIEF. Further automating and standardizing the diagnostic methods AI to identify abnormal Hbs would be a useful endeavor.

Single-stage Open Lobectomy and Modified Ravitch Procedure in an Infant with Coexisting Severe Pectus Excavatum and Congenital Cystic Adenomatous Malformation.

Coexisting congenital cystic adenomatous malformation of the lungs and severe pectus excavatum (PE) is an uncommon presentation that poses significant management challenges. Conventionally managed in a staged manner, there are increasing reports of superior outcomes with single-staged concurrent repair with minimally invasive techniques (video-assisted thoracoscopic surgery [VATS] and minimally invasive repair of PE [MIRPE]). The outcome of a single-stage open repair for both anomalies has not been previously reported to the best of our search.

Utilization and Findings of Flexible Naso-Pharyngo-Laryngoscopy in Upper Airway Disorders: A Clinic Audit.

Background: Flexible naso-pharyngo-laryngoscopy (NPL) has become an essential clinic tool for evaluating patients with upper airway disorders in otorhinolaryngology. It has been established to be a simple, cost-effective, and minimally invasive technique with good diagnostic yields. This study aimed to audit the procedure of flexible NPL done in our clinic over 2 years and analyse the technique, indications, and findings of the procedure.

Surveillance of from Diabetic Foot Infections in a Tunisian Hospital: Detection of ST131- and -ST1- Strains.

The study determined the prevalence, antimicrobial resistant (AMR) determinants, and genetic characteristics of and isolates from patients with diabetic foot infection (DFI) in a Tunisian hospital. A total of 26 spp. and spp.

The effects of selected neglected tropical diseases on economic performance at the macrolevel in Africa.

Background: Neglected tropical diseases (NTDs) such as leprosy, lymphatic filariasis (LF), schistosomiasis and onchocerciasis are endemic in several African countries. These diseases can lead to severe pain and permanent disability, which can negatively affect the economic productivity of the affected person(s), and hence resulting into low economic performance at the macrolevel. Nonetheless, empirical evidence of the effects of these NTDs on economic performance at the macrolevel is sparse.

Malaria Prevalence and Macroeconomic Output in Ghana, 1990 to 2019.

In Ghana, malaria remains the number 1 reason for outpatient department visits, making it a major public health problem. Thus, there could be significant lost productivity days as a result of malaria morbidity and mortality, which could negatively affect economic output at the macrolevel. Nonetheless, there is a dearth of empirical evidence of the effect of malaria on macroeconomic output in Ghana.

Towards a Distributed Digital Twin Framework for Predictive Maintenance in Industrial Internet of Things (IIoT).

This study uses a wind turbine case study as a subdomain of Industrial Internet of Things (IIoT) to showcase an architecture for implementing a distributed digital twin in which all important aspects of a predictive maintenance solution in a DT use a fog computing paradigm, and the typical predictive maintenance DT is improved to offer better asset utilization and management through real-time condition monitoring, predictive analytics, and health management of selected components of wind turbines in a wind farm. Digital twin (DT) is a technology that sits at the intersection of Internet of Things, Cloud Computing, and Software Engineering to provide a suitable tool for replicating physical objects in the digital space. This can facilitate the implementation of asset management in manufacturing systems through predictive maintenance solutions leveraged by machine learning (ML).

Primary gastroduodenal tuberculosis presenting as gastric outlet obstruction: A case report and review of literature.

Background: Mycobacterium tuberculosis (TB) is the causative agent of TB, a chronic granulomatous illness. This disease is prevalent in low-income countries, posing a significant global health challenge. Gastrointestinal TB is one of the three forms.

Rhino-Orbital Cerebral Mucormycosis in a Healthy Female Child: Case Report.

Mucormycosis is a potentially fatal condition with a high mortality rate, particularly when there is extra nasal involvement, and it is rare for patients with fungal brain disease to survive. It mostly affects patients who are metabolically or immunologically compromised, which constitutes one of the three classical stages of the progression of Rhino-Orbito-Cerebral Mucormycosis (ROCM). Stage I: infection of the nasal mucosa and paranasal sinuses; Stage II: orbital involvement; Stage III: cerebral involvement.

Tailored (LaPrNdTbDy)CeO as a Highly Active and Stable Nanocatalyst for the Oxygen Evolution Reaction.

Designing highly active and robust catalysts for the oxygen evolution reaction is key to improving the overall efficiency of the water splitting reaction. It has been previously demonstrated that evaporation induced self-assembly (EISA) can be used to synthesize highly porous and high surface area cerate-based fluorite nanocatalysts, and that substitution of Ce with 50% rare earth (RE) cations significantly improves electrocatalyst activity. Herein, the defect structure of the best performing nanocatalyst in the series are further explored, NdCeO, with a combination of neutron diffraction and neutron pair distribution function analysis.

Unexpected role of pig nostrils in the clonal and plasmidic dissemination of extended-spectrum beta-lactamase-producing Escherichia coli at farm level.

The presence of methicillin-resistant or -susceptible S. aureus in pig nostrils has been known for a long time, but the occurrence of extended-spectrum beta-lactamase (ESBL)-producing E. coli has hardly been investigated.

Substituent Impact on Quinoxaline Performance and Degradation in Redox Flow Batteries.

Aqueous redox flow batteries (RFBs) are attractive candidates for low-cost, grid-scale storage of energy from renewable sources. Quinoxaline derivatives represent a promising but underexplored class of charge-storing materials on account of poor chemical stability in prior studies (with capacity fade rates >20%/day). Here, we establish that 2,3-dimethylquinoxaline-6-carboxylic acid (DMeQUIC) is vulnerable to tautomerization in its reduced form under alkaline conditions.

Mesoporous RECeO Fluorite Electrocatalysts for the Oxygen Evolution Reaction.

Developing highly active and stable electrocatalysts for the oxygen evolution reaction (OER) is key to improving the efficiency and practical application of various sustainable energy technologies including water electrolysis, CO reduction, and metal air batteries. Here, we use evaporation-induced self-assembly (EISA) to synthesize highly porous fluorite nanocatalysts with a high surface area. In this study, we demonstrate that a 50% rare-earth cation substitution for Ce in the CeO fluorite lattice improves the OER activity and stability by introducing oxygen vacancies into the host lattice, which results in a decrease in the adsorption energy of the OH* intermediate in the OER.

Beyond the Wild MRSA: Genetic Features and Phylogenomic Review of -Mediated Methicillin Resistance in Non- Staphylococci and Mammaliicocci.

Methicillin resistance, mediated by the gene in staphylococci and mammaliicocci, has caused tremendous setbacks in the use of antibiotics in human and veterinary medicine due to its high potential of presenting the multidrug resistance (MDR) phenotype. Three other analogs exist, of which the has evolutionary been associated with methicillin-resistant (MRSA) in wild animals, thus loosely referred to as the wild MRSA. In this study, we present an epidemiological review and genomic analysis of non- staphylococci and mammaliicocci that carry the -mediated methicillin resistance trait and determine whether this trait has any relevant link with the One Health niches.