Publications by authors named "Abdullah Zia"
Availability of fresh water for domestic, industrial, and agricultural use has become a huge challenge in different parts of the world due to continuous contamination. The leaching of different pesticides in agricultural lands is one of the major sources of water contamination that needs to be monitored and countered. The current study was designed to synthesize specific material for the removal of pesticides from aqueous medium.
View Article and Find Full Text PDFBackground/objectives: Antisense oligonucleotide (ASO)-mediated exon-skipping is an effective approach to restore the disrupted reading frame of the dystrophin gene for the treatment of Duchenne muscular dystrophy (DMD). Currently, four FDA-approved ASOs can target three different exons, but these therapies are mutation-specific and only benefit a subset of patients. Understanding the broad applicability of exon-skipping approaches is essential for prioritizing the development of additional therapies with the greatest potential impact on the DMD population.
View Article and Find Full Text PDFBackground: Arglabin is a plant alkaloid (sesquiterpene lactone) that is used as an anticancer drug. It has potential anti-diabetic and anti-atherogenic effects.
Purpose: Arglabin has drawn particular attention because of its therapeutic effects as an anti-inflammatory agent in multiple diseases.
A 24-year-old man was referred to our tertiary care center for the management of uncontrolled hypertension secondary to severe coarctation of aorta.
View Article and Find Full Text PDFObjectives: The presentation and outcomes of acute decompensated heart failure (ADHF) during COVID times (June 2020 to Dec 2020) were compared with the historical control during the same period in 2019.
Methods: Data of 4806 consecutive patients of acute HF admitted in 22 centres in the country were collected during this period. The admission patterns, aetiology, outcomes, prescription of guideline-directed medical therapy (GDMT) and interventions were analysed in this retrospective study.
Article Synopsis
- - The growing need for sustainable aviation fuels (SAF) has led to the exploration of new technologies to use wet waste as a low-cost feedstock to create jet fuel alternatives, potentially replacing over 20% of US jet fuel consumption.
- - Researchers investigated the conversion of food waste into volatile fatty acids (VFAs) and their subsequent catalytic upgrading into n-paraffin and branched isoparaffin SAF blends, which meet fuel specifications and can significantly increase the renewable blend limits.
- - The study found that producing VFA-SAF from food waste could cut greenhouse gas emissions by up to 165% compared to traditional jet fuel, especially highlighting the economic feasibility and environmental benefits of diverting waste from landfills. *
The Interplay of Disease Modifying Anti Rheumatic Drugs and Tuberculin Skin Test.
Curr Rev Clin Exp Pharmacol
April 2022
Objective: The study was conducted to determine whether synthetic Disease-Modifying Anti Rheumatic Drugs (DMARDs) suppress the latency of Tuberculosis (TB) infection in Rheumatoid Arthritis (RA) patients along with other variables.
Methods: This was done through Tuberculin Skin Test (TST) using purified protein derivative (PPD) in a cohort of RA patients. The TST was taken positive when induration post-PPD injection was ≥ 5mm and negative or anergic when it was < 5mm.
Background: Early diagnosis and treatment of drug-resistant tuberculosis (TB) is crucial to halt the spread of drug resistance in the community.
Aim: The aim of the study was to compare rapid diagnostic tests (GeneXpert and line probe assay, LPA) with conventional liquid culture for the diagnosis of drug-resistant TB and to assess the risk factors for it.
Method: This cross-sectional study recruited 229 multidrug-resistant TB suspects who were sputum smear positive.