Pharmaceutical Advertising and Public Perceptions in Saudi Arabia.

Introduction: As the pharmaceutical advertising landscape evolves with digital advancements, this study examines public awareness and perceptions of medication advertisements in Saudi Arabia. It focuses on the effects of regulatory frameworks and evaluates how they influence public understanding and attitudes toward these advertisements.

Method: A cross-sectional study was conducted using an electronic survey in Saudi Arabia in December 2023.

Insights into Drug Donation Practices and Public Perceptions in Saudi Arabia.

Background: Effective medication management, disposal, and donation are vital for public health and environmental sustainability. Improper handling of medications can lead to drug misuse, accidental poisoning, and environmental damage. This study examines current practices and challenges in Saudi Arabia, identifying opportunities for improvement.

Insights into Pharmacists' Participation in Professional Certification Programs in Saudi Arabia.

Introduction: Professional certification programs play a crucial role in helping pharmacists develop specialized skills and establish their expertise in the field. This study explores how pharmacists in Saudi Arabia engage with these programs by examining their levels of awareness, attitudes, and participation. It also identifies the key barriers and motivators that influence their decision to pursue certification.

Can serum 17-hydroxy progesterone predict an improvement in semen parameters following micro-varicocelectomy? A prospective study.

Background & Objectives: Notably, 17-hydroxy progesterone (17-OHP) (17-OHP) is a precursor for testosterone (T) synthesis, and intratesticular testosterone (ITT) is essential for spermatogenesis. Varicocele (Vx) has an estimated prevalence of 15% in the general population and 35% in those with primary infertility. We aimed to evaluate the correlation between changes of serum 17-OHP after sub-inguinal micro-varicocelectomy and improvement of semen parameters.

Effective removal of textile dye via synergy of adsorption and photocatalysis over ZnS nanoparticles: Synthesis, modeling, and mechanism.

In this work, we prepared sulfur-zinc nanoparticles (ZnS-TGA) functionalized with thioglycolic acid by a hydrothermal method and tested their photodegradation ability by solar irradiation. ZnS-TGA were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), high-resolution transmission electron microscope (HR-TEM), UV-Vis spectrophotometer and photoluminescence spectroscopy. In the characterization of these nanoparticles, thioglycolic acid proved to be a strong capping ligand, with a specific surface area of 36.

Efficacy of forskolin as a promising therapy for chronic olfactory dysfunction post COVID-19.

Purpose: Olfactory dysfunction is increasingly common among COVID-19 patients, impacting their well-being. Reports have demonstrated decreased levels of cyclic adenosine monophosphate and cyclic guanosine monophosphate among patients with chronic olfactory dysfunction. A prospective randomized clinical trial was developed to demonstrate the efficacy of an oral forskolin regimen treatment, an adenylyl cyclase activator that raises intracellular levels of cyclic adenosine monophosphate, for the treatment of olfactory dysfunction following COVID-19, compared to placebo regimen.

Evaluating Adherence to Therapeutic Drug Monitoring Guidelines for Gentamicin in Neonatal Care: A Retrospective Study at the Maternity and Children's Hospital in Makkah.

In this study, we assess healthcare providers' adherence to therapeutic drug monitoring (TDM) guidelines for gentamicin in neonates. Conducted at the Maternity and Children's Hospital in Makkah, Saudi Arabia, from July 2020 to July 2022, it retrospectively analyzed the compliance of healthcare workers in managing neonates treated with gentamicin. Covering 410 neonates, primarily diagnosed with respiratory distress (56%) and sepsis (32%), the study revealed that while a majority of trough and peak levels conformed to guidelines, substantial deviations were noted in cases of respiratory distress.

Death and Venous Thromboembolism Analyses among Hospitalized COVID-19-Positive Patients: A Multicenter Study.

Background: Coagulation disorders are frequently encountered among patients infected with coronavirus disease 2019 (COVID-19), especially among admitted patients with more severe symptoms. This study aims to determine the mortality rate and incidence and risk factors for venous thromboembolism (VTE) in hospitalized patients with COVID-19.

Methods: This retrospective observational cohort study was conducted from March to July 2020 using a hospital database.

Spices as Sustainable Food Preservatives: A Comprehensive Review of Their Antimicrobial Potential.

Throughout history, spices have been employed for their pharmaceutical attributes and as a culinary enhancement. The food industry widely employs artificial preservatives to retard the deterioration induced by microbial proliferation, enzymatic processes, and oxidative reactions. Nevertheless, the utilization of these synthetic preservatives in food products has given rise to significant apprehension among consumers, primarily stemming from the potential health risks that they pose.

Overview of hypertension in Saudi Arabia: A systematic review and meta-analysis.

Objectives: To assess the prevalence, awareness, treatment, and control of hypertension in Saudi Arabia.

Methods: We searched electronic databases and the references lists of found publications between 1990 and 2022. Original cross-sectional studies in English were included using PubMed, Google Scholar, and the Saudi Digital Library.

Prevalence of Chronic Pain After Spinal Surgery: A Systematic Review and Meta-Analysis.

Degenerative disc disease and low back pain are common challenges that persist even after a discectomy. However, characterizations and quantifications of these illnesses from the patients' perspective are insufficient. We aimed to perform a systematic review of the literature and meta-analysis to determine the frequency of chronic pain after spinal surgery.

Artemisia sieberi Besser essential oil inhibits the growth and migration of breast cancer cells via induction of S-phase arrest, caspase-independent cell death and downregulation of ERK.

Ethnopharmacological Relevance: Artemisia sieberi Besser is a medicinal herb that has been traditionally used across the Middle East for the treatment of cancer. Further pharmacological studies on its extracts revealed that they possess cytotoxic activity against certain cancer cells, however, there were no studies conducted on the anticancer potential of Artemisia sieberi essential oil (ASEO).

Aim Of The Study: To evaluate the anticancer potential of ASEO, elucidate the oil's mode of action for the first time and investigate its chemical composition.

Gold Nanoparticle-Based Resuscitation of Cefoxitin against Clinical Pathogens: A Nano-Antibiotic Strategy to Overcome Resistance.

Gold nanoparticles have gained popularity as an effective drug delivery vehicle due to their unique features. In fact, antibiotics transported via gold nanoparticles have significantly enhanced their potency in the recent past. The present study used an approach to synthesize gold nanoparticles in one step with the help of cefoxitin antibiotic as a reducing and stabilizing agent.

Highlighting the adsorption mechanism of dyes onto activated carbon derived from sludge by theoretical physical analysis.

An activated carbon (AC) deriving from sludge is used in this research for the adsorption of two water pollutants, namely Reactive Black 5 (RB5) and Green Alizarin (GA) dyes, at different temperatures. The adsorption capacities varied from 277.2 to 312.

Social Differences in Health Behaviours among Jordanian Adolescents.

Social differences are evident in both developed and developing countries. During adolescence, there are limited differences in morbidity and mortality, but differences do appear in terms of health behaviours. This study aims to examine the relationship(s) between social differences and students' health behaviours.

A sex-stratified multiple regression on Jordanian adolescents' life satisfaction using different elements of school climate.

Background: School climate is one of several important factors influencing adolescent well-being and life satisfaction. Although a growing number of studies investigate the role of school climate, they often apply a global scale and only a few of them measure any specific elements. Likewise, most studies are focused on well-being and not life satisfaction.

Factors Associated With Adherence to COVID-19 Preventive Measures Among Saudi Arabians.

Background A recent outbreak of COVID-19 which was initially reported in Wuhan City, China, has become a worldwide pandemic. This global public health threat drew the attention of the medical and scientific community to make the necessary research efforts to combat the spread of the virus. Predictors of preventive behaviors could be of considerable importance relevant to identifying high-risk groups to manage their behavior.

ZnO nanodisk based UV detectors with printed electrodes.

The fabrication of highly functional materials for practical devices requires a deep understanding of the association between morphological and structural properties and applications. A controlled hydrothermal method to produce single crystal ZnO hexagonal nanodisks, nanorings, and nanoroses using a mixed solution of zinc sulfate (ZnSO4) and hexamethylenetetramine (HMTA) without the need of catalysts, substrates, or templates at low temperature (75 °C) is introduced. Metal-semiconductor-metal (MSM) ultraviolet (UV) detectors were fabricated based on individual and multiple single-crystal zinc oxide (ZnO) hexagonal nanodisks.

Hybrid graphene-metal oxide solution processed electron transport layers for large area high-performance organic photovoltaics.

Solution processed core-shell nano-structures of metal oxide-reduced graphene oxide (RGO) are used as improved electron transport layers (ETL), leading to an enhancement in photocurrent charge transport in PCDTBT:PC70 BM for both single cell and module photovoltaic devices. As a result, the power conversion efficiency for the devices with RGO-metal oxides for ETL increases 8% in single cells and 20% in module devices.

Role of the Exposed Polar Facets in the Performance of Thermally and UV Activated ZnO Nanostructured Gas Sensors.

ZnO nanostructures with different morphologies (nanowires, nanodisks, and nanostars) were synthesized hydrothermally. Gas sensing properties of the as-grown nanostructures were investigated under thermal and UV activation. The performance of the ZnO nanodisk gas sensor was found to be superior to that of other nanostructures ( ∼ 3700% to 300 ppm ethanol and response time and recovery time of 8 and 13 s).