Publications by authors named "Abdullah M T Al-Ibraheem"
Article Synopsis
- Obesity is a major global health issue, and effective prevention and treatment strategies, such as exercise and diet, are crucial in addressing it.
- This study reviews how exercise-induced cytokines, like IL-6 and BDNF, impact adipose tissue metabolism by enhancing fat oxidation and reducing fat storage, which can inform potential therapies.
- Key findings suggest that these cytokines influence energy expenditure and thermogenesis, indicating a complex relationship between exercise, inflammation, and fat metabolism that could lead to better obesity interventions.
Idiopathic pulmonary fibrosis: Addressing the current and future therapeutic advances along with the role of Sotatercept in the management of pulmonary hypertension.
Dalia D Hadi Mohammed Dheyaa Marsool Marsool Ali Dheyaa Marsool Marsool Neel Vora Sajjad G Al-Badri Abdullah M T Al-Ibraheem
Immun Inflamm Dis
November 2023
Article Synopsis
- Idiopathic pulmonary fibrosis (IPF) is a serious lung disease with no cure, causing irreversible lung scarring due to unknown genetic and environmental factors, and current treatments aim to slow progression and manage symptoms.
- Recent research explored new treatment options, including Saracatinib, which shows potential to be more effective than existing FDA-approved drugs for IPF, Pirfenidone and Nintedanib, and Sotatercept, which may help with pulmonary hypertension associated with the disease.
- This review highlights the potential for these advancements to improve IPF patient quality of life, but emphasizes the need for further studies to confirm their safety and efficacy.
Multiple sclerosis (MS) and myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) share the symptom of fatigue, and might even coexist together. Specifically focusing on genetics, pathophysiology, and neuroimaging data, the authors discuss an overview of the parallels, correlation, and differences in fatigue between MS and ME/CFS along with ME/CFS presence in MS. Studies have revealed that the prefrontal cortex and basal ganglia regions, which are involved in fatigue regulation, have similar neuroimaging findings in the brains of people with both MS and ME/CFS.
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