Publications by authors named "Abdullah M K Albloshi"
The postmortem interval (PMI) is one of the primary objectives and challenging tasks proposed for determining the time of death. This study aimed to estimate the PMI using serum levels of high mobility group box 1 (HMGB1), a biomarker of pyroptotic cell death, along with desmin immunohistochemical and histological analyses of the gastrocnemius muscle in rats at various time intervals. Serum and gastrocnemius muscle samples were collected at zero, 24-, 48-, 72-, and 96 hours postmortem from 50 rats maintained at 22 ± 2°C.
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- Genetic variability plays a crucial role in differences in skeletal muscle mass, but the specific genes responsible are not well understood; this study focuses on Rps6ka6 and Pou3f4 genes located on chromosome X in mice.
- The study involved analyzing muscle samples from male CFW mice with different alleles linked to muscle mass, revealing that the "increasing" allele led to larger muscle size and more muscle fibers, particularly in the fast-twitch extensor digitorum longus muscle.
- Findings suggest that Rps6ka6 influences muscle fiber count in fast-twitch muscles, whereas the Pou3f4 gene impacts fiber numbers in slow-twitch muscles, indicating distinct genetic roles in muscle development.
Infective endocarditis: Role of molecular techniques in early diagnosis.
Saudi J Biol Sci
December 2021
Infective endocarditis (IE), a heart valve infection primarily caused by bacteria such as or , causes significant morbidity and mortality. Despite the long-term use of broad-spectrum antimicrobials, the infection is often difficult to manage. The latest diagnostic modalities for IE are discussed in this study.
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