Nigella sativa ( ) is traditionally used as an immune enhancer in different communities. The aim of this study was to evaluate the effect of on immunity related parameters in young healthy subjects. This study was a double blind, randomized, placebo controlled clinical trial.
View Article and Find Full Text PDFInt J Environ Res Public Health
September 2022
Unlabelled: The current study investigated the impact of different doses of seeds on the symptoms, the cluster of differentiation profile group, and inflammatory markers of mild COVID-19 cases.
Methods: The study was a double-blind placebo-controlled clinical trial. Patients with mild and asymptomatic SARS-CoV-2 infection patients were randomly subdivided into seven subgroups: Group (GP) 1: received charcoal capsules as a control group, and GP 2: received three capsules of whole seeds daily, two capsules in the morning and one in the evening; GP 3: received three capsules of whole seeds every 12 h, GP 4: received five capsules in the morning and four capsules of whole seeds in the evening, GP 5: received one capsule of powder every 12 h; GP 6: received two capsules of powder every 12 h; GP 7: received three capsules of powder every 12 h; all treatment course was for ten days.
Background: There is substantial evidence that most SARS-CoV-2 infections are mild or even asymptomatic, yet they can transmit the virus to others. The current study described the clinical presentation of mild COVID-19 cases isolated in the ministry of health (MOH) quarantines in Riyadh, Saudi Arabia.
Methods: A cross-sectional study targeted the SARS-CoV-2 PCR +ve asymptomatic and mild COVID-19 patients isolated in the Saudi MOH quarantines in Riyadh city between July and December 2020.
Background: Fractional exhaled nitric oxide (FeNO) is a convenient to use biomarker of airway inflammation. However, the mutual relationship between FeNO, peripheral blood eosinophil, total immunoglobulin E (IgE) and inflammatory cytokines showed some controversy.
Objective: This study was carried out to determine the accuracy of peripheral blood eosinophil and total IgE to detect eosinophilic airway inflammation as determined by two FeNO cutoff points.
J Family Community Med
January 2019
Background: Methemoglobin (MetHb) level in blood indicates exposure to nitrogenous compounds. Acquired methemoglobinemia as a result of exposure to nitrates in drinking water is primarily an issue for infants. The amount of nitrates in Zamzam water is said to be on the high side.
View Article and Find Full Text PDFBackground: Nigella sativa and its derivatives have been reported to have anti-inflammatory and bronchodilator effects, but the effects have been evaluated in only a few clinical studies.
Objectives: To determine the effect of N sativa supplementation on inflammation of the airways and limitation of airflow in partly controlled asthma patients.
Design: Single-blind, placebo-controlled, randomized study.
Background: Diabetic patients with hypertension and dyslipidemia are at a high risk of cardiovascular complications.
Objectives: To determine the effect of Nigella sativa supplementation on the lipid profile, mean arterial pressure, and heart rate in persons with type 2 diabetes on oral hypoglycemic agents (OHA).
Design: Single-blind, nonrandomized.
Objectives: To study the effect of Nigella sativa supplementation on cardiac functions in Type 2 diabetic patients treated with oral hypoglycemic agents.
Background: Diabetes mellitus is associated with a high risk of cardiovascular morbidity and mortality. A number of reported beneficial effects of N.
Background And Objective: Oxidative stress plays an important role in pathogenesis of diabetes mellitus and its complications. Our previous study has shown glucose lowering effect produced by 3 months supplementation of Nigella sativa (NS) in combination with oral hypoglycemic drugs among type 2 diabetics. This study explored the long term glucose lowering effect (over one year) of NS in patients with type 2 diabetes mellitus on oral hypoglycemic drugs and to study its effect on redox status of such patients.
View Article and Find Full Text PDFExercise training is employed as supplementary therapeutic intervention for heart failure, due to its ability to induce physiological cardiac hypertrophy. In parallel, supplementation with Nigella sativa (N. sativa) was found to enhance myocardial function and induce cardiac hypertrophy.
View Article and Find Full Text PDFJ Family Community Med
September 2012
Background And Aim: The atherogenic pattern of dyslipidemia associated with type 2 diabetes mellitus (DM) has been increasingly discussed. We have recently reported a hypoglycemic effect of Nigella sativa (NS) seeds in patients with type 2 DM. In this study we sought to assess the impact of NS seeds on lipid profile in type 2 diabetic patients.
View Article and Find Full Text PDFIntermittent fasting (IF), a type of feeding regimen where the frequency of eating is reduced enhances cardiovascular stress adaptation and improves cardiovascular risk factors in rats. Data on the effect of IF on the endothelium is not common, so we examined whether IF showed similarity to documented beneficial effects of caloric restriction on endothelium-dependent vasodilatory responses of rat aortic rings. 25 young male Wistar rats had ad libitum (AL) access to food and 25 others were provided with food every other day for 2 months, during which their weight was measured every 2 weeks.
View Article and Find Full Text PDFUnlabelled: Diabetes mellitus is a common chronic disease affecting millions of people world wide. Standard treatment is failing to achieve required correction of blood glucose in many patients. Therefore, there is a need for investigating potential hypoglycemic drugs or herbs to improve glycemic control in diabetic patients.
View Article and Find Full Text PDFBackground/aim: A large number of diseases are ascribed to Helicobacter pylori (H. pylori), particularly chronic active gastritis, peptic ulcer disease and gastric cancer. Successful treatment of H.
View Article and Find Full Text PDFObjective: To study the effects of two, months Nigella sativa (N. sativa) oral supplementation to normal rats on cardiac haemodynamics in vivo, the ionotropic and chronotropic properties of the isolated hearts in vitro, and the cardiac responsiveness to progressive adrenergic stimulation by isoproterenol.
Methods: The cardiac workload, after 2 months of N.
Objectives: Exams are known to be strong external motivators for study. In this study, this observation was utilized to increase the attendance and attention of students in lectures.
Methodology: Tests were conducted at the end of every lecture, on the material covered in that lecture.
We have studied the effect of thymoquinone on the blood levels of cholesterol, triglycerides, HDL and LDL in albino rats. A total of 200 rats, 150 test group and 50 as controls, were included in the study. Six doses of thymoquinone (0.
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