Metabolic and behavioral effects of olanzapine and fluoxetine on the model organism .

The use of many psychotropic drugs (PDs) is associated with increased caloric intake, significant weight gain, and metabolic disorders. The nematode has been used to study the effects of PDs on food intake. However, little is known about PDs effects on the body fat of .

Early Exposure is Necessary for the Lifespan Extension Effects of Cocoa in .

Background: We previously showed that cocoa, a rich source of polyphenols improved the age-associated health and extended the lifespan in when supplemented starting from L1 stage.

Aim: In this study, we aimed to find out the effects of timing of cocoa exposure on longevity improving effects and the mechanisms and pathways involved in lifespan extension in .

Methods: The standard OP50 diet of wild type was supplemented with cocoa powder starting from different larval stages (L1, L2, L3, and L4) till the death, from L1 to adult day 1 and from adult day 1 till the death.

The Effect of Mianserin on Lifespan of Caenorhabditis elegan is Abolished by Glucose.

Background: The antidepressant Mianserin has been shown to extend the lifespan of Caenorhabditis elegan (C. elegan), a well-established model organism used in ageing research. The extension of lifespan in C.