Machine Learning in Intravascular Ultrasound: Validating Automated Lesion Assessment for Complex Coronary Interventions.

Background: Intravascular ultrasound (IVUS) is essential for assessing complex coronary lesions, but remains underutilized in part due to difficulties in image interpretation. The AVVIGO IVUS Automated Lesion Assessment (ALA) software, which uses machine learning (ML) for automatic segmentation, promises to simplify lesion assessment. This study evaluated the agreement in stent size selection between ALA, an independent core laboratory (CL), and an expert interventional cardiologist (IC) for complex lesions.

Bioprosthetic Aortic Valve Thrombosis: Definitions, Clinical Impact, and Management: A State-of-the-Art Review.

Bioprosthetic aortic valve thrombosis is frequently detected after transcatheter and surgical aortic valve replacement due to advances in cardiac computed tomography angiography technology and standardized surveillance protocols in low-surgical-risk transcatheter aortic valve replacement trials. However, evidence is limited concerning whether subclinical leaflet thrombosis leads to clinical adverse events or premature structural valve deterioration. Furthermore, there may be net harm in the form of bleeding from aggressive antithrombotic treatment in patients with subclinical leaflet thrombosis.

Postsurgical Transcatheter Mitral Valve Replacement.

Reintervention is commonly required postsurgical mitral valve replacement (SMVR) or repair due to bioprosthetic valve and annuloplasty ring degeneration. However, redo SMVR is associated with a high risk of morbidity and mortality. Postsurgical transcatheter mitral valve replacement (TMVR) is a safe and less-invasive alternative that has repeatedly been shown to be associated with improved survival and lower rates of complications compared with redo SMVR.

Rehabilitating simulated worn dentition by using a complete digital workflow and five anatomic guidelines.

This report describes the rehabilitation of worn dentition by using a complete digital workflow on a nonhinged simulated patient. A dentiform was used to represent an individual with loss of occlusal vertical dimension. Interim restorations were designed following the simulated patient's midline, interpupillary line, and ala-tragus line and a defined central incisal edge position, posterior maxillary teeth central groove, and buccal cusp position of posterior maxillary teeth.