Osseointegration of Tantalum Trabecular Metal in Titanium Dental Implants: Histological and Micro-CT Study.

This study aimed to investigate the impact of the Tantalum Trabecular Metal dental implant design on implant stability and the process of osseointegration following its placement in the rabbit femoral condyle. The subjects for the experiment consisted of 10 New Zealand white rabbits. Twenty implants, comprising 10 Trabecular Metal (TM) and 10 Traditional Screw Vent (TSV) implants, were placed into the femoral condyles of these rabbits.

Clinical outcomes of immediately loaded implant-supported overdentures: A long-term prospective clinical trial.

Statement Of Problem: Long-term evidence of immediate loading of dental implants with bar overdentures is lacking.

Purpose: The purpose of this clinical study was to assess the clinical outcomes of immediate and conventional loading protocols of mandibular overdentures supported by 2 dental implants 14 years after initial placement.

Material And Methods: Two groups of edentulous patients who received two TiUnite implants were enrolled in this study.

Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.

Membrane-bound proteinase 3 (PR3) is the main target antigen of anti-neutrophil cytoplasmic autoantibodies (ANCA) in granulomatosis with polyangiitis, a systemic small-vessel vasculitis. Binding of ANCA to PR3 triggers neutrophil activation with the secretion of enzymatically active PR3 and related neutrophil serine proteases, thereby contributing to vascular damage. PR3 and related proteases are activated from pro-forms by the lysosomal cysteine protease cathepsin C (CatC) during neutrophil maturation.

Analysis of urinary cathepsin C for diagnosing Papillon-Lefèvre syndrome.

Papillon-Lefèvre syndrome (PLS) (OMIM: 245000) is a rare disease characterized by severe periodontitis and palmoplantar keratoderma. It is caused by mutations in both alleles of the cathepsin C (CatC) gene CTSC that completely abrogate the proteolytic activity of this cysteine proteinase. Most often, a genetic analysis to enable early and rapid diagnosis of PLS is unaffordable or unavailable.

Accuracy of interchangeable implant impression systems: an in vitro pilot study.

Purpose: To evaluate the accuracy of impressions on changing the implant component (coping and abutment replica) between Brånemark and BIOMET 3i and between Straumann and Allfit.

Materials And Methods: Two master casts were constructed, one containing pair of Brånemark self-tap Mk II fixtures (Nobel Biocare) labeled Master cast I and the other containing pair of Straumann Standard plus implant, SLA fixtures (Straumann) labeled Master cast II. Ten impressions of each master cast were made by open tray technique using polyether impression material.

Effects of calcium phosphate composition in sputter coatings on in vitro and in vivo performance.

Calcium phosphate (CaP) ceramic coatings have been used to enhance the biocompatibility and osteoconductive properties of metallic implants. The chemical composition of these ceramic coatings is an important parameter, which can influence the final bone performance of the implant. In this study, the effect of phase composition of CaP-sputtered coatings was investigated on in vitro dissolution behavior and in vivo bone response.

Osseointegration of oral implants after delayed placement in rabbits: a microcomputed tomography and histomorphometric study.

Purpose: This study compared osseointegration of implants placed 14 days after implant site preparation with that of immediately placed implants in rabbit femurs.

Materials And Methods: Implants were placed bilaterally in the femoral condyles of 12 rabbits. On one side, the implants were placed 14 days after osteotomy, and the other side received implants immediately after osteotomy.

The influence of implant geometry and surface composition on bone response.

Objectives: The implant design and surface modification are independent conditions that can alter the implant bone response. The objective of this study is to compare the bone response to roughened tapered and cylindrical screw-type implants with and without hydroxyapatite (HA) surface coating in the femoral trabecular bone of rabbits.

Material And Method: Thirty-two implants (8 × 3.

Oral rehabilitation of a case of Papillon-Lefevre syndrome with dental implants.

Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder characterized by diffuse palmoplantar keratoderma and precocious aggressively progressing periodontitis, leading to the premature loss of deciduous and permanent teeth. Full mouth rehabilitation with implant supported fixed prosthesis provides numerous advantages over the conventional denture in terms of esthetics, function, longevity of the prosthesis, and patient satisfaction. We report a case of PLS in a 19-year-old female who underwent extraction of all the teeth followed by full mouth rehabilitation with implant supported fixed prostheses.

Resolution, sensitivity, and in vivo application of high-resolution computed tomography for titanium-coated polymethyl methacrylate (PMMA) dental implants.

Objectives: The aims of this study were (i) to determine the spatial resolution and sensitivity of micro- versus nano-computed tomography (CT) techniques and (ii) to validate micro- versus nano-CT in a dog dental implant model, comparative to histological analysis.

Material And Methods: To determine spatial resolution and sensitivity, standardized reference samples containing standardized nano- and microspheres were prepared in polymer and ceramic matrices. Thereafter, 10 titanium-coated polymer dental implants (3.

In vivo evaluation of bioactive glass-based coatings on dental implants in a dog implantation model.

Objectives: Although titanium is commonly used as a favorable bone implant material due to its mechanical properties, its bioactive and osteoconductive capacity is relatively low. Calcium phosphate ceramics, predominantly hydroxyapatite (HA), have been frequently used for coating purposes to improve the bioactive properties. In view of the suggested osteopromotive capacity of bioactive glasses (BGs), this study aimed to evaluate the effect of BG incorporation into HA coatings on implant performance in terms of bone contact and bone area.

Biological response to titanium implants coated with nanocrystals calcium phosphate or type 1 collagen in a dog model.

Objective: The current study aimed to evaluate the osteogenic potential of electrosprayed organic and non-organic surface coatings in a gap-implant model over 4 and 12 weeks of implantation into the dog mandible.

Material And Methods: Sixteen Beagle dogs received experimental titanium implants in the mandible 3 months after removal of left premolars (P2, P3 and P4). Three types of implants were installed in each animal: non-coated implant, nano-CaP coated implant and implant with type 1 collagen coating.

Study of the osseointegration of dental implants placed with an adapted surgical technique.

Objective: To study the osseointegration of dental implants placed with a modified surgical technique in Beagle dogs and to compare it with the conventional method.

Materials And Methods: Dental implants were placed bilaterally in the mandible of Beagle dogs using the press-fit as well as undersized implant bed preparation technique. Micro computer tomography (micro-CT) and histometric methods were used to analyze the bone implant contact and bone volume (BV) around the implants.