Atomic-layer-deposition application for antibacterial coating of biomedical materials: surgical sutures.

Suture-associated surgical site infection (SSI) causes bacterial pathogens to colonize on the suture surface that are highly resistant to antibiotic treatment. Conventional suture materials used in surgical practice are causing complications such as infection and chronic inflammation. Surgical suture materials with antibacterial coatings are widely used in surgical practice.

Immunotherapy of inflammatory bowel disease (IBD) through mesenchymal stem cells.

Many pathophysiologic pathways and immune-pathologic etiologies are addressed as Inflammatory bowel disease (IBD) causes. Moreover, dysfunction of the immune system leads to inflammatory responses against intestinal components that boost disease severity. The use of routine treatments has limitations.

ALD coated polypropylene hernia meshes for prevention of mesh-related post-surgery complications: an experimental study in animals.

In this work, thermal atomic layer deposition (ALD) was used to synthesize vanadium (V)-doped TiOthin nanofilm on polypropylene (PP) hernia meshes. Multiple layers of (AlO+ TiVO) nano-films were coated on the PP hernia mesh surface to provide a layer with a total thickness of 38 nm to improve its antibacterial properties, thereby, prevent mesh-related post-surgery complications. Highly conformal V-doped TiOnanofilm were deposited on PP mesh at a temperature of 85 °C.

Composition of essential oils from four Apiaceae and Asteraceae species growing in Uzbekistan.

The chemical composition of essential oils isolated from the aerial parts of Heracleum lehmannianum, Prangos pabularia, Pseudohandelia umbellifera and Pulicaria salviifolia, all of them growing in Uzbekistan, were determined by GC-MS analysis. The main components of the oil from H. lehmannianum were α-phellandrene (10.

[Morphological changes in airway tissues in patients with laryngeal and tracheal deformations].

A histomorphological picture of surgically removed cicatricial tissue was compared in two groups of patients with deformations of the larynx and trachea: operated within 1-2 months after trauma and 6-12 months after it. Chronic productive inflammation was found in the tissue early after trauma, while later, mature scar tissue was forming. The conclusion is made that operation early after trauma in combination with conservative therapy may prevent deformation and dystrophic changes in the cartilages as well as development of scar tissue.

[Pathogenic mechanisms of the wound process in persistent deformities of the larynx and trachea].

The examination of 67 patients with persistent deformities of the larynx and trachea has revealed mixed aerobic-anaerobic flora affecting healing of postoperative laryngeal wounds as it gives rise to chronic inflammatory infiltration, tissue dystrophy and deteriorates hemocirculation. The above data will be helpful in development indications and contraindications for various reconstructive operations.