Exposure to PFAS such as GenX (HFPO dimer acid) has become increasingly common due to the replacement of older generation PFAS in manufacturing processes. While neurodegenerative and developmental effects of legacy PFAS exposure have been studied in depth, there is a limited understanding specific to the effects of GenX exposure. To investigate the effects of GenX exposure, we exposed to GenX and assessed the motor behavior and performed quantitative proteomics of fly brains to identify molecular changes in the brain.
View Article and Find Full Text PDFSeveral reports highlighted the central role of inflammation in the pathogenesis of corona virus disease-19 (COVID-19) disease. Also, the hyper-inflammatory response that is triggered by severe acute respiratory syndrom-Covid-2 (SARS-CoV-2) infection was believed to play an essential role in disease severity and adverse clinical course. For that reason, the classical inflammatory markers were proposed as a possible indicator for COVID-19 severity.
View Article and Find Full Text PDFObjective: To determine the degree of contamination caused by parasites in commonly used leafy vegetables in Abha, Kingdom of Saudi Arabia (KSA).
Methods: We carried out the study in the Department of Clinical Microbiology and Parasitology, King Khalid University, Abha, KSA, during the period September 2004 to May 2005. Five commonly used leafy vegetables, namely, green onion, radish, watercress, lettuce and leek, were washed each in water and Tris-buffer-saline (TBS).