Amphotericin B Polymer Nanoparticles Show Efficacy against Species Biofilms.

Purpose: Chronic infections of are characterised by the embedding of budding and entwined filamentous fungal cells into biofilms. The biofilms are refractory to many drugs and biofilms are associated with ocular fungal infections. The objective was to test the activity of nanoparticulate amphotericin B (AmB) against biofilms.